Protein Alignment Trc8 and AMFR

DIOPT Version :9

• Sequence 1: NP_996303.1
• Gene: Trc8 / 43476
• FlyBaseID: FBgn0039668
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_001310441.1
• Gene: AMFR / 267
• HGNCID: 463
• Length: 675
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 93/414 - (22%)
• Similarity: 152/414 - (36%)
• Gaps: 93/414 - (22%)

  Fly   399 LFYILALQTGLTSLSPDKRFIRLCRNLCLLMTALLHFLHNIV---SPILMSLSAARNPSRKRHVR 460
            :||......|:.::...:..:..|     |..|.|.|||.:|   ......||.:.......|.|
Human   126 IFYKFIFIFGVLNVQTVEEVVMWC-----LWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGR 185

  Fly   461 ALSV--------CAFLVVLSVSLLYHLWSQQSISTWLLAVTAFSVEVVVKVLVSLATYTLFLLDA 517
            .||:        |....|.|::...|     .:.| |..:.|.|:.|.|:....:..|.:.|.|.
Human   186 VLSLLVAMLLSCCGLAAVCSITGYTH-----GMHT-LAFMAAESLLVTVRTAHVILRYVIHLWDL 244

  Fly   518 RRQFFWEKLDDYLYYVRAFGNSVEFCFGILLFINGAWILIFESAQNATGGGIRAIMMCIH--AYF 580
            ..:..||....|:||..              |:....:|..:            :|..||  .:.
Human   245 NHEGTWEGKGTYVYYTD--------------FVMELTLLSLD------------LMHHIHMLLFG 283

  Fly   581 NIWCEARAGWSVFMKRRSAVHKI------------------SALPEATPAQLQAFDDVCAICYQE 627
            |||. :.|...:||:.|...|::                  :....|||.:|...:|.||||:..
Human   284 NIWL-SMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARFAVATPEELAVNNDDCAICWDS 347

  Fly   628 MYSAKITRCRHFFHGVCLRKWLYVQDRCPLCHEIMMYTDKADENAPEAEP---------APAAQA 683
            |.:|:...|.|.||..|||.||.....||.|.   |..:.||.|....|.         .|.|.|
Human   348 MQAARKLPCGHLFHNSCLRSWLEQDTSCPTCR---MSLNIADNNRVREEHQGENLDENLVPVAAA 409

  Fly   684 EQPMRIYPRD-----DANNAAAQRRSPERAPVEASEQAPATSSSSAAATIGAEAVSAIVESAAAV 743
            |...|:...:     |.::::.:..:||..||  .::.....|.:.|..:.:...|.:...:..|
Human   410 EGRPRLNQHNHFFHFDGDDSSMRVTAPEDVPV--GQEVEVVDSDTDAPDLWSRIASWLPSFSVEV 472

  Fly   744 GEARSLVSVASSSSA-----THRI 762
            ....:::.:..:|::     .|:|
Human   473 MHTTNILGITQASNSQLNAMAHQI 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trc8	NP_996303.1	TRC8_N	122..590	CDD:290425	44/203 (22%)
		zf-rbx1	<618..659	CDD:289448	18/40 (45%)
		zf-RING_2	619..659	CDD:290367	18/39 (46%)
AMFR	NP_001310441.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D897451at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820