Protein Alignment Trc8 and sel-11

DIOPT Version :10

• Sequence 1: NP_996303.1
• Gene: Trc8 / 43476
• FlyBaseID: FBgn0039668
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_505969.1
• Gene: sel-11 / 179612
• WormBaseID: WBGene00004768
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 127/595 - (21%)
• Similarity: 193/595 - (32%)
• Gaps: 189/595 - (31%)

  Fly   359 AVLGMTGVISMFCHYIGRGFQWY-------LLTYDDEEKSLGTVSAVLFYILALQTGLTSLSPDK 416
            ||:.:.|::.::..     ||..       |...:.|..|..|..|||...||    .|....|.
 Worm    45 AVIYVQGIVLVYLM-----FQLLKSILFGDLRAAEAEHLSERTWHAVLETCLA----FTVFRDDF 100

  Fly   417 RFIRLCRNLCLLMTALLHFLHNIVSPILMSLSAARNP--SRKRHVRALSVCA---FLVVLSVSLL 476
            ..|.:.:.:.||.....|:|.:....::     .|:|  :.:.|:|.::|.|   |.....||..
 Worm   101 SAIFVMQFIGLLFIKCFHWLADDRVDMM-----ERSPVITLRFHLRMMTVLAALGFADSYFVSSA 160

  Fly   477 YHLWSQQSISTWLLAVTAFSVEVVVKVLVSLA-TYTLFLLDARRQFFWEKLDDYLYYVRAFGNSV 540
            |.....:..|..:  |..|...:::.:::.:. .|.|.:.|.|....|:....||.|..
 Worm   161 YFTTITRGASAQI--VFGFEYAILLALVLHVTIKYLLHMHDLRNPQSWDNKAVYLLYAE------ 217

  Fly   541 EFCFGILLFINGAWILIFESAQNATGGGIRAIMMCIHA---------YFNIWCEARAGWSVFMKR 596
                   ||||....|::        |....:|:.:|.         |.::....:|...|.:.|
 Worm   218 -------LFINLIRCLLY--------GFFAVVMLRVHTFPLFSVRPFYQSVRALHKAFLDVILSR 267

  Fly   597 RSAVHKISALPEATPAQLQAFDDVCAICYQEM---YSAKITRCRHFFHGVCLRKWLYVQDRCPLC 658
            |:.....|..|..:...|.|.|..|.||.:||   .|.|...|.|.||..|||.|...|..||.|
 Worm   268 RAINAMNSQFPVVSAEDLAAMDATCIICREEMTVDASPKRLPCSHVFHAHCLRSWFQRQQTCPTC 332

  Fly   659 HEIMMYTD--------------------KADENAPEAE--------------------------- 676
            .     ||                    .||.|...|:
 Worm   333 R-----TDIWQGRNGAAAGGNAADAAANVADANVAGAQIGAGMPPFLPFLGHQFGFPQQPAGAGG 392

  Fly   677 ----------------------PAPAAQAE-------------QPMRIYPR------DDANNAAA 700
                                  ||||.:.|             .|..::|.      ...|  ..
 Worm   393 AQPGAAQAGGQPGPFPHQIFYAPAPANRPEFMNLIPPPPLPMAGPPGMFPMMPPPPLPQVN--TT 455

  Fly   701 QRRSPERAPVEASEQAPAT---------SSSSAAATIGA-EAVSAIVESA-------AAVGEARS 748
            |..|.|..||..|....:|         |..:..|.:.| :.:..::|||       |.|...|.
 Worm   456 QGTSSETPPVNPSYSQLSTEELRRMEGESREALLARLQAMDNIMVLLESAQMQMIQLATVTPIRP 520

  Fly   749 LVSVASS--------------SSATHRISASGSSDSSYMTASAQSPPPTATSAAAVATAAASNTT 799
            ...|.|.              :|....|.|:.|:.|.:.|.| .|...||.|.::..||:::.||
 Worm   521 RPVVPSDESEQEAPGPSTDQVTSEEQEIPATSSAPSIFRTES-PSTSSTAPSTSSPVTASSTPTT 584

  Fly   800 HMFRMSQDQQ 809
            ...|..:.::
 Worm   585 SSTRTPEAEE 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trc8	NP_996303.1	TRC8_N	8..590	CDD:463960	52/252 (21%)
		RING-H2_RNF139-like	619..659	CDD:438139	18/42 (43%)
sel-11	NP_505969.1	HRD1	51..>333	CDD:227568	76/318 (24%)