Protein Alignment FipoQ and GRR1

DIOPT Version :10

• Sequence 1: NP_733291.1
• Gene: FipoQ / 43475
• FlyBaseID: FBgn0039667
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_012623.1
• Gene: GRR1 / 853552
• SGDID: S000003850
• Length: 1151
• Species: Saccharomyces cerevisiae
• Alignment Length: 558
• Identity: 114/558 - (20%)
• Similarity: 203/558 - (36%)
• Gaps: 152/558 - (27%)

  Fly    34 IEKLPDKVLLHIFSYLSHREICRLARICR---RWRQIAYDTR---LWKNVSLRPEVSGLHVG--- 89
            |..|..|:|..|..|..     .|...|.   |.:|:...|.   :|.|.....|.|.|..|
Yeast   224 IRNLRLKILTIIEEYKK-----SLYAYCHSKLRGQQVENPTDNFIIWINSIDTTESSDLKEGLQD 283

  Fly    90 ----SLEMLLQLIS-----------VRFGPTLRYIELPIELITHTVLHELSAKCPNLTHMLLDFS 139
                |.:.:..::|           .|..|......||.|:: |.:|.:|:.|     :.::.|.
Yeast   284 LSRYSRQFINNVLSNPSNQNICTSVTRRSPVFALNMLPSEIL-HLILDKLNQK-----YDIVKFL 342

  Fly   140 TAMQL---------------HDFSEMQAFPTKLRYMCVCLSEVIFMEGFMRKIYNF------ING 183
            |..:|               :..|::..|   ||.|.:...|.:|....|.|..||      ::.
Yeast   343 TVSKLWAEIIVKILYYRPHINKKSQLDLF---LRTMKLTSEETVFNYRLMIKRLNFSFVGDYMHD 404

  Fly   184 LEVLHLIGTYEKCEEEEE------------EIYEVINVHKLKSATPNLRVINLYGINFIDDSHID 236
            .|:.:.:|    |:..|.            .|..|:...|.      |:.:::.||..:.|...|
Yeast   405 TELNYFVG----CKNLERLTLVFCKHITSVPISAVLRGCKF------LQSVDITGIRDVSDDVFD 459

  Fly   237 AFSSNCIQLECLAVNFCNKVTGSTLKTLIQRSKRLTCLLMNGTSLKSEFVMQAEWDKC-ALQELD 300
            ..::.|.:::...|.....||..:|:..|..|..|..:.:...:..::.:::...:|| .|.|:|
Yeast   460 TLATYCPRVQGFYVPQARNVTFDSLRNFIVHSPMLKRIKITANNNMNDELVELLANKCPLLVEVD 524

  Fly   301 IT-ATDLSTECLVDMLSRIPSLKFLSAGQINGFNDSVLKQWMESGTTRSLISLDLDSSDNISDEG 364
            || :.:::...|:.:|:|:..|:...........|::.:                :.|..:.|..
Yeast   525 ITLSPNVTDSSLLKLLTRLVQLREFRITHNTNITDNLFQ----------------ELSKVVDDMP 573

  Fly   365 LLKFIQRQGHQLSACCLSGMPHITDQLWMSILPL--------LGNCKIIV---MGTAEKLGVNIH 418
            .|:.|.          |||..:|||:...||:.|        ||.|..|.   :....|||.|:.
Yeast   574 SLRLID----------LSGCENITDKTIESIVNLAPKLRNVFLGKCSRITDASLFQLSKLGKNLQ 628

  Fly   419 VDQLMDTIASNCGNLERLELRWDPDNLRFSDKSQKAI--DILRVKCLKLRCMV-LSDGRYYETVK 480
            ....     .:|.|:              :|...:|:  ...|::.:...|.. |::...||.
Yeast   629 TVHF-----GHCFNI--------------TDNGVRALFHSCTRIQYVDFACCTNLTNRTLYEL-- 672

  Fly   481 ANFERADRITVVRTTTCCRVSPYHL-----LRNYNDLI 513
            |:..:..||.:|:   |.:::...|     ||..||.:
Yeast   673 ADLPKLKRIGLVK---CTQMTDEGLLNMVSLRGRNDTL 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..78	CDD:463757	13/49 (27%)
		ING	110..>166	CDD:355795	15/70 (21%)
		leucine-rich repeat	131..156	CDD:275381	5/39 (13%)
		leucine-rich repeat	157..175	CDD:275381	5/17 (29%)
		leucine-rich repeat	219..244	CDD:275381	6/24 (25%)
		leucine-rich repeat	245..270	CDD:275381	6/24 (25%)
		leucine-rich repeat	271..295	CDD:275381	3/24 (13%)
		leucine-rich repeat	296..320	CDD:275381	8/24 (33%)
		leucine-rich repeat	321..348	CDD:275381	2/26 (8%)
		leucine-rich repeat	349..375	CDD:275381	4/25 (16%)
		leucine-rich repeat	376..403	CDD:275381	11/34 (32%)
GRR1	NP_012623.1	F-box-like	320..361	CDD:463757	10/46 (22%)
		AMN1	404..559	CDD:187754	31/164 (19%)
		leucine-rich repeat	416..441	CDD:275381	3/24 (13%)
		leucine-rich repeat	442..467	CDD:275381	6/24 (25%)
		leucine-rich repeat	494..519	CDD:275381	3/24 (13%)
		leucine-rich repeat	520..545	CDD:275381	8/24 (33%)
		leucine-rich repeat	546..574	CDD:275381	4/43 (9%)
		AMN1	<574..737	CDD:187754	38/168 (23%)
		leucine-rich repeat	575..600	CDD:275381	11/34 (32%)
		leucine-rich repeat	601..626	CDD:275381	7/24 (29%)
		leucine-rich repeat	627..652	CDD:275381	4/43 (9%)
		leucine-rich repeat	653..677	CDD:275381	5/25 (20%)
		leucine-rich repeat	678..704	CDD:275381	7/28 (25%)
		leucine-rich repeat	707..732	CDD:275381	0/1 (0%)