DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and Fbxl22

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_780415.1	Gene:	Fbxl22 / 74165	MGIID:	1921415	Length:	236	Species:	Mus musculus

Alignment Length:	243	Identity:	51/243 - (20%)
Similarity:	78/243 - (32%)	Gaps:	76/243 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IEKLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVSLRPEVSGLHVGSLEMLLQLI 98
            |.:|..:.||.:||:|.......|:|.|.:.|.:..|..||..         ||..||.. |:..
Mouse     3 ITQLNRECLLCLFSFLDKDSRRSLSRTCSQLRDVFEDPTLWPL---------LHFHSLAE-LKKD 57

  Fly    99 SVRFGPTLRYIELPIELITHTVLHELSAKCPNLTHMLLDFSTAMQLHDFSEMQAFPTKLRYMCVC 163
            :.|..|.||    .:.:..|:                            |.:|          ||
Mouse    58 NFRLSPALR----SLSICWHS----------------------------SRVQ----------VC 80

  Fly   164 LSEVIFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIYEVINVHKLK--SATPNLRVINLYG 226
            ..|........|.|                  |.:.|    .::|...|:  :..|||..:.|.|
Mouse    81 SIEDWLKSALQRSI------------------CSQHE----SLVNDFLLQVCNRCPNLTSVTLSG 123

  Fly   227 INFIDDSHIDAFSSNCIQLECLAVNFCNKVTGSTLKTLIQRSKRLTCL 274
            ...:.|..:.....:|.:|..|.:..|.:||..||..:....:.|..|
Mouse   124 CGHVTDDCLARLLLSCPRLRTLRLENCARVTNRTLAAVAAHGRALQTL 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	14/45 (31%)
		leucine-rich repeat	131..156	CDD:275381	2/24 (8%)
		leucine-rich repeat	157..175	CDD:275381	3/17 (18%)
		leucine-rich repeat	219..244	CDD:275381	5/24 (21%)
		leucine-rich repeat	245..270	CDD:275381	7/24 (29%)
		leucine-rich repeat	271..295	CDD:275381	2/4 (50%)
		leucine-rich repeat	296..320	CDD:275381
		leucine-rich repeat	321..348	CDD:275381
		leucine-rich repeat	349..375	CDD:275381
		leucine-rich repeat	376..403	CDD:275381
		leucine-rich repeat	405..432	CDD:275381
Fbxl22	NP_780415.1	F-box-like	3..43	CDD:403981	12/39 (31%)
		LRR 1	15..40		7/24 (29%)
		LRR 2	43..72		10/42 (24%)
		AMN1	45..>200	CDD:187754	37/201 (18%)
		LRR 3	98..123		7/28 (25%)
		leucine-rich repeat	116..141	CDD:275381	5/24 (21%)
		LRR 4	124..149		4/24 (17%)
		leucine-rich repeat	142..167	CDD:275381	7/24 (29%)
		LRR 5	150..175		7/22 (32%)
		leucine-rich repeat	168..193	CDD:275381	2/4 (50%)
		LRR 6	176..201
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843092
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830