DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FipoQ and fbxl7

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001073511.1	Gene:	fbxl7 / 569430	ZFINID:	ZDB-GENE-061215-122	Length:	489	Species:	Danio rerio

Alignment Length:	477	Identity:	101/477 - (21%)
Similarity:	189/477 - (39%)	Gaps:	148/477 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IEKLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVSLRPEVSGLHVGSLEMLLQLI 98
            ::.|||...|.||::|...::||.||:||||..:|:|.|||:.:.|..:|  |||   :..|:::
Zfish   112 VDILPDHAFLQIFTHLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGDV--LHV---DRALRVL 171

  Fly    99 SVRF---------------------------------GPTLRYIELP-IELITHTVLHELSAKCP 129
            :.|.                                 .|.||.:|:. ...:::..:.|:.::||
Zfish   172 TRRLCQDTPNVCLTVETVMVSGCRRLTDRGLYTVAQSCPELRRLEVAGCYNVSNEAVFEVVSRCP 236

  Fly   130 NLTHMLLDFSTAMQLHDFSEMQAFPTKLRYMCVCLSEVIFMEGFMRKIYNFINGLEVLHLIGTYE 194
            ||.|  ||.|...::               .|:.|:..:.::            |..||
Zfish   237 NLEH--LDVSGCSKV---------------TCISLTRDVSVK------------LSPLH------ 266

  Fly   195 KCEEEEEEIYEVINVHKLKSATPNLRVINLYGINFIDDSHIDAFSSNCIQLECLAVNFCNKVTGS 259
                 .::|              ::|.:::.....::|..:...:::|.||..|.:..|.::|..
Zfish   267 -----GQQI--------------SIRFLDMTDCFALEDEGLHTIAAHCTQLTHLYLRRCVRLTDE 312

  Fly   260 TLKTLIQRSKRLTCLLMNGTSLKSEFVMQAEWDKC--ALQELDIT----ATDLSTECLVDMLSRI 318
            .|:.|:.....:..|.::.....|:|.:: |..|.  .|:.|.|.    .||:....:....||
Zfish   313 GLRFLVIYCPGVRELSVSDCRFISDFGLR-EIAKLEGRLRYLSIAHCSRITDVGVRYVAKYCSR- 375

  Fly   319 PSLKFLSAGQINGFNDSVLKQWMESGTTRSLISLDLDSSDNISDEGLLKFIQRQGHQLSACCLSG 383
              |::|:|....|..|..::...:|  ...|.|||:.....:||.||
Zfish   376 --LRYLNARGCEGLTDHGIEHLAKS--CLKLKSLDIGKCPLVSDAGL------------------ 418

  Fly   384 MPHITDQLWMSILPLLGNCKIIVMGTAEKL-GVNIHVDQLMDTIASNCGNLERLELRWDPDNLRF 447
                 :||.::..    |.|.:.:.:.|.: |..:.|      :|:||.:|:.|       |::.
Zfish   419 -----EQLALNSF----NLKRLSLKSCESITGRGLQV------VAANCFDLQLL-------NVQD 461

  Fly   448 SDKSQKAIDILRVKCLKLRCMV 469
            .|.|.:|:..::..|  .||::
Zfish   462 CDVSLEALRFVKRHC--KRCII 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	20/45 (44%)
		leucine-rich repeat	131..156	CDD:275381	5/24 (21%)
		leucine-rich repeat	157..175	CDD:275381	2/17 (12%)
		leucine-rich repeat	219..244	CDD:275381	3/24 (13%)
		leucine-rich repeat	245..270	CDD:275381	6/24 (25%)
		leucine-rich repeat	271..295	CDD:275381	5/25 (20%)
		leucine-rich repeat	296..320	CDD:275381	7/27 (26%)
		leucine-rich repeat	321..348	CDD:275381	6/26 (23%)
		leucine-rich repeat	349..375	CDD:275381	8/25 (32%)
		leucine-rich repeat	376..403	CDD:275381	3/26 (12%)
		leucine-rich repeat	405..432	CDD:275381	6/27 (22%)
fbxl7	NP_001073511.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..76
		F-box-like	112..158	CDD:289689	20/45 (44%)
		leucine-rich repeat	127..151	CDD:275381	11/23 (48%)
		leucine-rich repeat	152..185	CDD:275381	8/37 (22%)
		LRR 1	168..193		2/24 (8%)
		AMN1	<183..364	CDD:187754	38/235 (16%)
		leucine-rich repeat	186..211	CDD:275381	0/24 (0%)
		LRR 2	194..219		4/24 (17%)
		leucine-rich repeat	212..233	CDD:275381	4/20 (20%)
		LRR 3	220..245		8/26 (31%)
		leucine-rich repeat	238..271	CDD:275381	11/86 (13%)
		LRR 4	251..279		7/64 (11%)
		leucine-rich repeat	272..297	CDD:275381	3/24 (13%)
		LRR 5	280..305		5/24 (21%)
		AMN1	295..463	CDD:187754	47/213 (22%)
		leucine-rich repeat	298..323	CDD:275381	6/24 (25%)
		LRR 6	306..331		5/24 (21%)
		leucine-rich repeat	324..349	CDD:275381	5/25 (20%)
		LRR 7	332..357		7/25 (28%)
		leucine-rich repeat	350..375	CDD:275381	5/24 (21%)
		LRR 8	358..383		7/27 (26%)
		leucine-rich repeat	376..401	CDD:275381	6/26 (23%)
		LRR 9	384..409		7/26 (27%)
		leucine-rich repeat	402..427	CDD:275381	10/51 (20%)
		LRR 10	410..435		8/51 (16%)
		leucine-rich repeat	428..451	CDD:275381	5/28 (18%)
		LRR 11	436..461		9/37 (24%)
		leucine-rich repeat	454..478	CDD:275381	7/32 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588100
Domainoid	1	1.000	58	1.000	Domainoid score	I10759
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750