DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and fbxl22

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001013297.1	Gene:	fbxl22 / 503591	ZFINID:	ZDB-GENE-050227-1	Length:	227	Species:	Danio rerio

Alignment Length:	304	Identity:	66/304 - (21%)
Similarity:	105/304 - (34%)	Gaps:	99/304 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVSLRPEVSGLHVGSLEMLLQLISV 100
            :|..:.|||:||||.......|:..|.|.||:..|.:||         :.||..| ...|:..:.
Zfish     5 ELDQECLLHLFSYLDKDSRRSLSLTCVRLRQVFLDPQLW---------TLLHFWS-PCELRRDNF 59

  Fly   101 RFGPTLRYIELPIELITHTVLHELSAKCPNLTHMLLDFSTAMQLHDFSEMQAFPTKLRYMCVCLS 165
            ..|.:|||:.:        ..|....|..|:.|.:   .|..|..                :|..
Zfish    60 VVGSSLRYLAV--------CWHSSRVKVCNIEHWM---KTTFQKD----------------LCSK 97

  Fly   166 EVIFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIYEVINVHKLKSATPNLRVINLYGINFI 230
            ...|:..|:..:.|.               |                    |||..:.|.|...|
Zfish    98 HESFVSDFLEHVCNM---------------C--------------------PNLISLTLSGCGHI 127

  Fly   231 DDSHIDAFSSNCIQLECLAVNFCNKVTGSTLKTLIQRSKRLTCLLMNGTSLKSEF---VMQAEWD 292
            .|:::.....:|.:|..|::..|.::|.|.||..::....|       |.::.:|   |.||
Zfish   128 MDNNVIKVLQSCRRLRSLSLENCARITDSVLKAAVEHGHNL-------TEVRVDFCRNVTQA--- 182

  Fly   293 KCALQELD----------ITATDLSTECLVDMLSRIPSL--KFL 324
              .||||.          :.:.|:..:|..:..:.|...  |||
Zfish   183 --GLQELKNKKPEVLLSALHSADMIPDCKPEEKTHIKRALQKFL 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	16/43 (37%)
		leucine-rich repeat	131..156	CDD:275381	3/24 (13%)
		leucine-rich repeat	157..175	CDD:275381	3/17 (18%)
		leucine-rich repeat	219..244	CDD:275381	6/24 (25%)
		leucine-rich repeat	245..270	CDD:275381	7/24 (29%)
		leucine-rich repeat	271..295	CDD:275381	6/26 (23%)
		leucine-rich repeat	296..320	CDD:275381	7/33 (21%)
		leucine-rich repeat	321..348	CDD:275381	3/6 (50%)
		leucine-rich repeat	349..375	CDD:275381
		leucine-rich repeat	376..403	CDD:275381
		leucine-rich repeat	405..432	CDD:275381
fbxl22	NP_001013297.1	F-box-like	9..48	CDD:289689	16/47 (34%)
		AMN1	<103..>191	CDD:187754	28/134 (21%)
		leucine-rich repeat	116..141	CDD:275381	6/24 (25%)
		leucine-rich repeat	142..167	CDD:275381	7/24 (29%)
		leucine-rich repeat	168..187	CDD:275381	8/30 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587995
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930