DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and Lrrc29

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	XP_006255593.1	Gene:	Lrrc29 / 502201	RGDID:	1593150	Length:	673	Species:	Rattus norvegicus

Alignment Length:	493	Identity:	101/493 - (20%)
Similarity:	180/493 - (36%)	Gaps:	126/493 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RSPFAD---------------TTIEKL--PDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRL 73
            ||.|:|               |.::.|  ..::|.:|.|:|...:....:.:.|.|...|.:...
  Rat    29 RSQFSDILRPRGIGSKALRVLTPLKHLIFSPQMLTYILSFLPLSDQKEASLVSRAWYYAAQNALR 93

  Fly    74 WKNVSLRPEVSGLHVGSLEML-------LQLISVRFGPTLRYIELPIELITHTVLHELSAKC-PN 130
            ..||.....||...:.:::.|       :.|.::...|.           :|.||..::... |:
  Rat    94 ETNVRYNIPVSSASLSAIKSLGRRGISCISLTNLDGSPA-----------SHQVLQSVAYHLGPH 147

  Fly   131 LTHMLLDFSTAMQLHDFSEMQAFPTKLRYMCVCLSEVIFMEGFMRKIYNFINGLEVLHLIGTYEK 195
            |..:.|...:             ||:..::.:.|...:     :|.:  .::|...|...||...
  Rat   148 LQSLCLGGGS-------------PTEASFLALILGCPV-----LRTL--DLSGCNSLFTSGTLLA 192

  Fly   196 CEEEEEEIYEVINVHKLKSATPNLRVINLYGINFIDDSHIDAFSSNCIQLECLAVNFCN------ 254
            ..|..:.:         :.|...||.:||.|:..:.|...:..||....||.|::.:|:
  Rat   193 QPETAQCV---------RKALSGLRDLNLAGLRDLTDLSFNHLSSCFPSLERLSLAYCHLTFELG 248

  Fly   255 KVTGST---------------LKTLIQRSKRLTCLLMNGTSLKSEFVMQA--EWDKCALQELDI- 301
            ...|||               |:.:.:|:..|..|.::||.|..| .:||  :.....|:||::
  Rat   249 STWGSTSPQASSPSQLSFHNLLQFIKERAGTLRALDLSGTGLPPE-ALQALGQVTGLKLEELNLN 312

  Fly   302 TATDLSTECLVDMLSRIPSLKFLSAGQINGFNDSVLKQWMESGTTRSLISLDLDSSDNISDEGLL 366
            :..|||:|.:..:..:.|.|..|.....:...|..|  ...|.....|..|.|.....::|.|.:
  Rat   313 SCKDLSSEAVATLCRQQPGLTSLDLSGCSELTDRAL--LAVSRGLHHLRHLSLKKLQRLTDAGCI 375

  Fly   367 ---KFIQRQGHQLSACCL-SGM-------------PHIT-----------DQLWMSILPLLG-NC 402
               ...:.|...::.||| ||.             |.:|           |...:|::|.|| :.
  Rat   376 ALGALHELQSLDMAECCLVSGRELAQVLGSVRRAPPALTSLRLAYCSSLKDASVLSMIPALGPSL 440

  Fly   403 KIIVMGTAEKLGVNIHVDQLMDTIASNCGNLERLELRW 440
            |::.:.:...|     .:|.|..|.:...:|..|.|.|
  Rat   441 KVLDLSSCVAL-----TNQTMQAICTYLIHLSVLRLAW 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	10/47 (21%)
		leucine-rich repeat	131..156	CDD:275381	3/24 (13%)
		leucine-rich repeat	157..175	CDD:275381	1/17 (6%)
		leucine-rich repeat	219..244	CDD:275381	8/24 (33%)
		leucine-rich repeat	245..270	CDD:275381	9/45 (20%)
		leucine-rich repeat	271..295	CDD:275381	8/25 (32%)
		leucine-rich repeat	296..320	CDD:275381	7/24 (29%)
		leucine-rich repeat	321..348	CDD:275381	5/26 (19%)
		leucine-rich repeat	349..375	CDD:275381	6/28 (21%)
		leucine-rich repeat	376..403	CDD:275381	12/52 (23%)
		leucine-rich repeat	405..432	CDD:275381	4/26 (15%)
Lrrc29	XP_006255593.1	leucine-rich repeat	124..142	CDD:275381	5/28 (18%)
		LRR_RI	<170..410	CDD:238064	56/258 (22%)
		leucine-rich repeat	173..206	CDD:275381	7/43 (16%)
		leucine-rich repeat	207..232	CDD:275381	8/24 (33%)
		leucine-rich repeat	233..279	CDD:275381	9/45 (20%)
		leucine-rich repeat	280..300	CDD:275381	8/20 (40%)
		AMN1	292..480	CDD:187754	43/190 (23%)
		leucine-rich repeat	306..331	CDD:275381	7/24 (29%)
		leucine-rich repeat	332..357	CDD:275381	5/26 (19%)
		leucine-rich repeat	358..439	CDD:275381	18/80 (23%)
		leucine-rich repeat	383..408	CDD:275381	6/24 (25%)
		leucine-rich repeat	413..437	CDD:275381	4/23 (17%)
		leucine-rich repeat	440..465	CDD:275381	5/29 (17%)
		leucine-rich repeat	466..526	CDD:275381	4/8 (50%)
		leucine-rich repeat	527..577	CDD:275381
		AMN1	<564..>638	CDD:187754
		leucine-rich repeat	578..603	CDD:275381
		leucine-rich repeat	604..629	CDD:275381
		leucine-rich repeat	630..655	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346584
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830