DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and Fbxl16

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	XP_038942467.1	Gene:	Fbxl16 / 494223	RGDID:	1309127	Length:	488	Species:	Rattus norvegicus

Alignment Length:	464	Identity:	104/464 - (22%)
Similarity:	175/464 - (37%)	Gaps:	105/464 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LAVEASQVYL-------SDGTVRSPFADTTIEKLP----DKVLLHIFSYLSHREICRLARICRRW 64
            ||...|:|.|       :.|....|.....:|:.|    :|:|..:|.|.|..|.|.||::|:.|
  Rat    60 LATPLSRVALAGGPCPPASGPASGPVPGPPVERPPLATDEKILNGLFWYFSACEKCILAQVCKAW 124

  Fly    65 RQIAYDTRLWKNVSLRPEVSGLHVGSLEMLL-----QLISVRFGPTLRYIE---------LPI-E 114
            |::.|..:.|  ..|.|.   ||...|..:|     :.:::: |...|..|         |.| |
  Rat   125 RRVLYQPKFW--AGLTPV---LHAKELYNVLPGGEKEFVNLQ-GFAARGFEGFCLVGVSDLDICE 183

  Fly   115 LITHTVLHELSAKCPNLTH----------MLLDFSTAMQL-----HDFSEMQAFPT-KLRYMCVC 163
            .|.:..|.:...|..:|..          ||......::|     :||:|...:.: ..|...:.
  Rat   184 FIDNYSLSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLS 248

  Fly   164 LSEVI-----FMEGFMRKIYNFIN-GLEVLHLIGT---YEKCEEEEE-------EIYEVIN---- 208
            :|:.|     .:....:.:.|... .|:..|:..|   |....:...       ..:|:.|
  Rat   249 VSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVV 313

  Fly   209 --VHKLKSATPNLRVINLYGINFIDDSHIDAFSSNCIQLECLAVNFCNKVTGSTLKTLIQRSKRL 271
              ||.|    |||..::|.|.:.:.|..::..:.|..:|..|.:::|.::|...|:.:.....||
  Rat   314 NVVHSL----PNLTSLSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRL 374

  Fly   272 TCLLMNGTSLKSEFVMQAEWDKCALQE-----LDITATDLSTECLVDMLSRIPSLKFLSAGQING 331
            ..|::               |:|....     :.||.|.||   .:..:|.:.||......|:..
  Rat   375 EELVL---------------DRCTHPYTPGWCVRITDTGLS---YLSTMSSLRSLYLRWCCQVQD 421

  Fly   332 FNDSVLKQWMESGTTRSLISLDLDSSDNISDEGLLKFIQRQGHQLSACCLSGMPHITDQLWMSIL 396
            |.   ||..:   ..|||..|.|.....::..||...:|.|  :|....|:..|..|.:|:....
  Rat   422 FG---LKHLL---AMRSLRLLSLAGCPLLTTTGLSGLVQLQ--ELEELELTNCPGATPELFKYFS 478

  Fly   397 PLLGNCKII 405
            ..|..|.:|
  Rat   479 QHLPRCLVI 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	16/49 (33%)
		leucine-rich repeat	131..156	CDD:275381	7/40 (18%)
		leucine-rich repeat	157..175	CDD:275381	3/22 (14%)
		leucine-rich repeat	219..244	CDD:275381	5/24 (21%)
		leucine-rich repeat	245..270	CDD:275381	5/24 (21%)
		leucine-rich repeat	271..295	CDD:275381	3/23 (13%)
		leucine-rich repeat	296..320	CDD:275381	6/28 (21%)
		leucine-rich repeat	321..348	CDD:275381	5/26 (19%)
		leucine-rich repeat	349..375	CDD:275381	7/25 (28%)
		leucine-rich repeat	376..403	CDD:275381	6/26 (23%)
		leucine-rich repeat	405..432	CDD:275381	1/1 (100%)
Fbxl16	XP_038942467.1	leucine-rich repeat	195..219	CDD:275381	4/23 (17%)
		AMN1	201..422	CDD:187754	45/242 (19%)
		leucine-rich repeat	220..243	CDD:275381	4/22 (18%)
		leucine-rich repeat	244..269	CDD:275381	2/24 (8%)
		leucine-rich repeat	270..321	CDD:275381	9/54 (17%)
		leucine-rich repeat	322..347	CDD:275381	5/24 (21%)
		leucine-rich repeat	348..373	CDD:275381	5/24 (21%)
		leucine-rich repeat	374..407	CDD:275381	9/50 (18%)
		leucine-rich repeat	408..427	CDD:275381	6/21 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810