DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and Fbxl2

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	XP_038938600.1	Gene:	Fbxl2 / 363156	RGDID:	1562243	Length:	439	Species:	Rattus norvegicus

Alignment Length:	470	Identity:	105/470 - (22%)
Similarity:	169/470 - (35%)	Gaps:	162/470 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SQVYLSDGTVRSPFADTTIEKLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVSL- 79
            |.|.|...|...|..|.::...|     .|||:|....:||.|:|.:.|..:|.|...|:.|.|
  Rat    15 SPVSLRTRTGSDPRIDVSLVHGP-----RIFSFLDIVTLCRCAQISKAWNILALDGSNWQRVDLF 74

  Fly    80 --RPEVSGLHVGSLEMLLQLISVRFGPTLRYIELPIELITHTVLHELSAKCPNLTHMLLDFSTAM 142
              :.:|.|                                 .|:..:|.:|
  Rat    75 NFQTDVEG---------------------------------RVVENISKRC-------------- 92

  Fly   143 QLHDFSEMQAFPTKLRYMCVCLSEVIFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIYEVI 207
                                        .||:||
  Rat    93 ----------------------------GGFLRK------------------------------- 98

  Fly   208 NVHKLKSATPNLRVINLYGINFIDDSHIDAFSSNCIQLECLAVNFCNKVTGSTLKTLIQRSKRL- 271
                          ::|.|...:.||.:..|:.||..:|.|.:|.|.|:|.||..:|.:...:|
  Rat    99 --------------LSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLK 149

  Fly   272 -----TCLLMNGTSLK--SEFVMQAEWDKCALQELDITATDLSTECLVDMLSR-IPSLKFLSAGQ 328
                 :|:.:..:|||  ||.....|:       |:::..|..|:..::.|.| ...||.|....
  Rat   150 HLDLTSCVSVTNSSLKGISEGCRNLEY-------LNLSWCDQITKEGIEALVRGCRGLKALLLRG 207

  Fly   329 INGFNDSVLKQWMESGTTRSLISLDLDSSDNISDEGLLKFIQRQGHQLSACCLSGMPHITDQLWM 393
            .....|..||.....  ...|:||:|.|...|:|:|::: |.|..|:|.|.||||..::||
  Rat   208 CTQLEDEALKHIQNH--CHELVSLNLQSCSRITDDGVVQ-ICRGCHRLQALCLSGCSNLTD---- 265

  Fly   394 SILPLLG-NCKIIVMGTAEKLGVNIHV-DQLMDTIASNCGNLERLELRWDPDNLRFSDKSQKAID 456
            :.|..|| ||..:.:..|.:..   |: |.....:|.||.:||:::|.   :.:..:|.:   :.
  Rat   266 ASLTALGLNCPRLQVLEAARCS---HLTDAGFTLLARNCHDLEKMDLE---ECVLITDST---LI 321

  Fly   457 ILRVKCLKLRCMVLS 471
            .|.:.|.||:.:.||
  Rat   322 QLSIHCPKLQALSLS 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	15/48 (31%)
		leucine-rich repeat	131..156	CDD:275381	0/24 (0%)
		leucine-rich repeat	157..175	CDD:275381	2/17 (12%)
		leucine-rich repeat	219..244	CDD:275381	7/24 (29%)
		leucine-rich repeat	245..270	CDD:275381	9/24 (38%)
		leucine-rich repeat	271..295	CDD:275381	8/31 (26%)
		leucine-rich repeat	296..320	CDD:275381	5/24 (21%)
		leucine-rich repeat	321..348	CDD:275381	6/26 (23%)
		leucine-rich repeat	349..375	CDD:275381	10/25 (40%)
		leucine-rich repeat	376..403	CDD:275381	12/27 (44%)
		leucine-rich repeat	405..432	CDD:275381	6/27 (22%)
Fbxl2	XP_038938600.1	F-box-like	<38..72	CDD:403981	12/33 (36%)
		leucine-rich repeat	68..95	CDD:275381	8/101 (8%)
		AMN1	<92..239	CDD:187754	46/242 (19%)
		leucine-rich repeat	96..115	CDD:275381	6/63 (10%)
		leucine-rich repeat	122..147	CDD:275381	9/24 (38%)
		leucine-rich repeat	148..173	CDD:275381	7/24 (29%)
		leucine-rich repeat	174..199	CDD:275381	6/31 (19%)
		AMN1	184..383	CDD:187754	49/169 (29%)
		leucine-rich repeat	200..225	CDD:275381	6/26 (23%)
		leucine-rich repeat	226..251	CDD:275381	10/25 (40%)
		leucine-rich repeat	252..277	CDD:275381	13/28 (46%)
		leucine-rich repeat	278..303	CDD:275381	6/27 (22%)
		leucine-rich repeat	304..329	CDD:275381	6/30 (20%)
		leucine-rich repeat	330..352	CDD:275381	3/7 (43%)
		leucine-rich repeat	359..378	CDD:275381
		leucine-rich repeat	384..409	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346642
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840