DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and CG9003

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001097271.1	Gene:	CG9003 / 36244	FlyBaseID:	FBgn0033639	Length:	651	Species:	Drosophila melanogaster

Alignment Length:	470	Identity:	111/470 - (23%)
Similarity:	187/470 - (39%)	Gaps:	137/470 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EASQVYLSDGTVRSPFADTTIEKLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVS 78
            :.||.:|.    .:...|..|::||.:|||.:||||....:||.|::|:.|..:|.|...|:.::
  Fly   224 DQSQTFLG----ATELDDELIKQLPKEVLLRVFSYLDVVSLCRCAQVCKYWNVLALDGSSWQKIN 284

  Fly    79 L---RPEVSGLHVGSLEMLLQLISVRFGPTLRYIEL-PIELITHTVLHELSAKCPNLTHM----- 134
            |   :.::.|       .:::.||.|....|:.:.| ..:.:....:..|:..|.|:.|:
  Fly   285 LFDFQRDIEG-------PVIENISQRCRGFLKSLSLRGCQSVGDQSVRTLANHCHNIEHLDLSDC 342

  Fly   135 --LLDFS-----------TAMQLHDFSEMQAFPTKLRYM---CVCLSEV------IFMEGFMRKI 177
              :.|.|           ||:.||..|.:.  ...|:|:   |..|.|:      :..|
  Fly   343 KKITDISTQSISRYCSKLTAINLHSCSNIT--DNSLKYLSDGCPNLMEINVSWCHLISE------ 399

  Fly   178 YNFINGLEVLHLIGTYEKCEEEEEEIYEVIN---VHKLKSATPNLRVINLYGINFIDDSHIDAFS 239
                ||:|.  |.....|..:...:..:.||   :..|....|:|.|:||:....|.||.|...:
  Fly   400 ----NGVEA--LARGCVKLRKFSSKGCKQINDNAIMCLAKYCPDLMVLNLHSCETITDSSIRQLA 458

  Fly   240 SNCIQLECLAVNFCNKVTGSTLKTLIQRSKRLTCLLMNGTSLKSEFVMQA-----------EWDK 293
            :||.:|:.|.|:.|..:|..||.:|.|.:..|..|.::|....::...||           :.::
  Fly   459 ANCHKLQKLCVSKCADLTDLTLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEE 523

  Fly   294 CALQELDITATDLSTECLVDMLSRIPSLKFLSAGQINGFNDSVLKQWMESGTTRSLISLDLDSSD 358
            |: |..|:|...|:|.|        |||:                            .|.|...:
  Fly   524 CS-QITDLTLAHLATGC--------PSLE----------------------------KLTLSHCE 551

  Fly   359 NISDEGLLKFIQRQGHQLSACCLSGMPHITDQLWMSILPLLGNCKIIVMGTAEKLGVNIHVDQLM 423
            .|:|:|:       .|..:..|.:.:        :|:|. |.||.:|...|.|.|
  Fly   552 LITDDGI-------RHLTTGSCAAEI--------LSVLE-LDNCPLITDRTLEHL---------- 590

  Fly   424 DTIASNCGNLERLEL 438
                .:|.||:|:||
  Fly   591 ----VSCHNLQRIEL 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	19/48 (40%)
		leucine-rich repeat	131..156	CDD:275381	8/42 (19%)
		leucine-rich repeat	157..175	CDD:275381	6/26 (23%)
		leucine-rich repeat	219..244	CDD:275381	10/24 (42%)
		leucine-rich repeat	245..270	CDD:275381	9/24 (38%)
		leucine-rich repeat	271..295	CDD:275381	5/34 (15%)
		leucine-rich repeat	296..320	CDD:275381	6/23 (26%)
		leucine-rich repeat	321..348	CDD:275381	1/26 (4%)
		leucine-rich repeat	349..375	CDD:275381	5/25 (20%)
		leucine-rich repeat	376..403	CDD:275381	5/26 (19%)
		leucine-rich repeat	405..432	CDD:275381	5/26 (19%)
CG9003	NP_001097271.1	F-box-like	240..285	CDD:289689	18/44 (41%)
		leucine-rich repeat	280..307	CDD:275381	6/33 (18%)
		AMN1	<308..453	CDD:187754	34/158 (22%)
		leucine-rich repeat	308..327	CDD:275381	2/18 (11%)
		leucine-rich repeat	334..359	CDD:275381	3/24 (13%)
		leucine-rich repeat	360..385	CDD:275381	8/26 (31%)
		leucine-rich repeat	386..411	CDD:275381	7/36 (19%)
		AMN1	<409..586	CDD:187754	52/229 (23%)
		leucine-rich repeat	412..437	CDD:275381	3/24 (13%)
		leucine-rich repeat	438..463	CDD:275381	10/24 (42%)
		leucine-rich repeat	464..515	CDD:275381	14/50 (28%)
		leucine-rich repeat	516..541	CDD:275381	7/33 (21%)
		leucine-rich repeat	542..561	CDD:275381	6/53 (11%)
		leucine-rich repeat	571..595	CDD:275381	10/38 (26%)
		leucine-rich repeat	596..621	CDD:275381	4/6 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457971
Domainoid	1	1.000	41	1.000	Domainoid score	I4815
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840