DRSC/TRiP Functional Genomics Resources

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Protein Alignment FipoQ and fbxl14a

DIOPT Version :9

Sequence 1:NP_733291.1 Gene:FipoQ / 43475 FlyBaseID:FBgn0039667 Length:515 Species:Drosophila melanogaster
Sequence 2:NP_958890.1 Gene:fbxl14a / 333988 ZFINID:ZDB-GENE-030131-5920 Length:411 Species:Danio rerio


Alignment Length:486 Identity:112/486 - (23%)
Similarity:185/486 - (38%) Gaps:137/486 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 IEKLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVSLRPEVSGLHV--------GS 90
            |..|..::|..||:||..:...|:|::|..||..:|...:|:.|..:     ||:        .|
Zfish     5 ISSLFPEILAMIFNYLDVKGKGRVAQVCTAWRDASYHKSVWRGVEAK-----LHLRRANPSLFPS 64

  Fly    91 LE----MLLQLISVRFGPTLRYIELPIELITHTVLHELSAKCPNLTHMLLDFSTAMQLHDFSEMQ 151
            |:    ..:|::|:|  .:|.|:   |:.:.:.....||. |.|||...|.       |.|  :|
Zfish    65 LQTRGIKKVQILSLR--RSLSYV---IQGMPNIESLNLSG-CYNLTDNGLG-------HAF--VQ 114

  Fly   152 AFPTKLRYMCVCLSEVIFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIYEVINVHKLKSA- 215
            ..|: ||.:.:.|.:.| .:..:.:|..::..||:|.|.|    |.       .:.|...|..| 
Zfish   115 DIPS-LRILNLSLCKQI-TDSSLGRIAQYLKNLELLDLGG----CS-------NITNTGLLLIAW 166

  Fly   216 -TPNLRVINLYGINFIDD---SHIDAF----SSNCIQLECLAVNFCNKVTGSTLKTLIQRSKRLT 272
             ..||:.:||.....:.|   .|:...    :..|:.||.|.:..|.|:|..:||.:   ||.|.
Zfish   167 GLHNLKSLNLRSCRHVSDVGIGHLAGMTRSAAEGCLTLEHLTLQDCQKLTDLSLKHI---SKGLN 228

  Fly   273 CLLMNGTSLKSEFVMQAEWDKCALQELDITATDLSTECLVDMLSRIPSLKFLSAGQINGFNDSVL 337
                                                           .||.|:.....|.:|:.:
Zfish   229 -----------------------------------------------KLKVLNLSFCGGISDAGM 246

  Fly   338 KQWMESGTTRSLISLDLDSSDNISDEGLLKF----IQRQGHQLSACCLSG---MPHITDQLWMSI 395
               :.......|.:|:|.|.|||||.|::..    ::..|..:|.|...|   :.:|...|:.  
Zfish   247 ---IHLSHMTQLWTLNLRSCDNISDTGIMHLSMGALRLYGLDVSFCDKVGDQSLAYIAQGLYQ-- 306

  Fly   396 LPLLGNCKIIVMGTAEKLGVNIHVDQLMDTIASNCGNLER-----LELRWDP-------DNLRFS 448
            |..|..|...:...    |:|..|.|:.:....|.|...|     |||..|.       |....:
Zfish   307 LKSLSLCSCHISDD----GINRMVRQMHELKTLNIGQCVRITDKGLELIADHLTQLTGIDLYGCT 367

  Fly   449 DKSQKAID-ILRVKCLKLRCMVLSDGRYYET 478
            ..:::.:: |.::.|||    ||:.|.:..|
Zfish   368 KITKRGLERITQLPCLK----VLNLGLWQMT 394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FipoQNP_733291.1 F-box-like 34..80 CDD:289689 15/45 (33%)
leucine-rich repeat 131..156 CDD:275381 7/24 (29%)
leucine-rich repeat 157..175 CDD:275381 4/17 (24%)
leucine-rich repeat 219..244 CDD:275381 6/31 (19%)
leucine-rich repeat 245..270 CDD:275381 9/24 (38%)
leucine-rich repeat 271..295 CDD:275381 1/23 (4%)
leucine-rich repeat 296..320 CDD:275381 0/23 (0%)
leucine-rich repeat 321..348 CDD:275381 5/26 (19%)
leucine-rich repeat 349..375 CDD:275381 11/29 (38%)
leucine-rich repeat 376..403 CDD:275381 7/29 (24%)
leucine-rich repeat 405..432 CDD:275381 5/26 (19%)
fbxl14aNP_958890.1 F-box-like 5..46 CDD:289689 13/40 (33%)
AMN1 90..243 CDD:187754 47/225 (21%)
leucine-rich repeat 92..118 CDD:275381 10/35 (29%)
leucine-rich repeat 119..144 CDD:275381 5/25 (20%)
leucine-rich repeat 145..170 CDD:275381 9/35 (26%)
leucine-rich repeat 171..203 CDD:275381 6/31 (19%)
leucine-rich repeat 204..229 CDD:275381 11/74 (15%)
AMN1 230..397 CDD:187754 44/178 (25%)
leucine-rich repeat 230..254 CDD:275381 5/26 (19%)
leucine-rich repeat 255..280 CDD:275381 10/24 (42%)
leucine-rich repeat 281..304 CDD:275381 5/22 (23%)
leucine-rich repeat 307..331 CDD:275381 7/27 (26%)
leucine-rich repeat 332..357 CDD:275381 7/24 (29%)
leucine-rich repeat 358..377 CDD:275381 1/18 (6%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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