DRSC/TRiP Functional Genomics Resources

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Protein Alignment FipoQ and Fbxl12

DIOPT Version :9

Sequence 1:NP_733291.1 Gene:FipoQ / 43475 FlyBaseID:FBgn0039667 Length:515 Species:Drosophila melanogaster
Sequence 2:NP_001273458.1 Gene:Fbxl12 / 30843 MGIID:1354738 Length:349 Species:Mus musculus


Alignment Length:386 Identity:80/386 - (20%)
Similarity:132/386 - (34%) Gaps:127/386 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 LPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVSL-----RPEVSGLHVGSLEMLLQ 96
            ||.:.:|     |.....|   |:|.||:::..|..||::|.|     ||:|. .|:....|..:
Mouse    38 LPSQTIL-----LPRNPGC---RVCHRWKRLVDDRWLWRHVDLTLYTMRPKVM-WHLLRRYMASR 93

  Fly    97 LISVRFGPTLRYIELPIELITHTVLHELSAKCPNLTHMLL---DFS-----------TAMQLHD- 146
            |.|:|.|..| :.......::..::..|..|||||..:.|   |.|           ..::||. 
Mouse    94 LYSLRMGGYL-FSGSQAPQLSPALMRALGQKCPNLKRLCLHVADLSMVPITSLPSTLRTLELHSC 157

  Fly   147 -----FSEMQAFPTKLRYM-CVCLSEV-IFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIY 204
                 :.:.:..||.|..: |:.|..| .|.:..::.:..| ..|..|.|.|||.          
Mouse   158 EISMIWLQKEQDPTVLPLLECIVLDRVPAFRDEHLQGLTRF-RALRSLVLGGTYR---------- 211

  Fly   205 EVINVHKLKSATPNLRVINLYGINFIDDSHIDAFSSNCIQLECLAVNFCNKVTGSTLKTLIQ--R 267
                                     :.::.:||.......|:.|.|..|.....|||..:.:  |
Mouse   212 -------------------------VTETGLDASLQELSYLQRLEVLGCTLSADSTLLAISRHLR 251

  Fly   268 SKRLTCLLMNGTS------LKSEFVMQAEWDKCALQELDI-TATDLSTECLVDMLSRIPSLKFLS 325
            ..|...|.:.|.|      |:...|:::...:..|...|: |.|.:.:.||.     :|.|:.| 
Mouse   252 DVRKIRLTVGGLSAQGLVFLEGMPVLESLCFQGPLITPDMPTPTQIVSSCLT-----MPKLRVL- 310

  Fly   326 AGQINGFNDSVLKQWMESGTTRSLISLDLDSSDNISDEGLLKFIQRQGHQLSACCLSGMPH 386
              ::.|..      |                               :|.:.......|:||
Mouse   311 --EVQGLG------W-------------------------------EGQEAEKILCKGLPH 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FipoQNP_733291.1 F-box-like 34..80 CDD:289689 14/47 (30%)
leucine-rich repeat 131..156 CDD:275381 7/44 (16%)
leucine-rich repeat 157..175 CDD:275381 5/19 (26%)
leucine-rich repeat 219..244 CDD:275381 2/24 (8%)
leucine-rich repeat 245..270 CDD:275381 8/26 (31%)
leucine-rich repeat 271..295 CDD:275381 5/29 (17%)
leucine-rich repeat 296..320 CDD:275381 6/24 (25%)
leucine-rich repeat 321..348 CDD:275381 4/26 (15%)
leucine-rich repeat 349..375 CDD:275381 1/25 (4%)
leucine-rich repeat 376..403 CDD:275381 3/11 (27%)
leucine-rich repeat 405..432 CDD:275381
Fbxl12NP_001273458.1 F-box-like <51..73 CDD:289689 9/24 (38%)
leucine-rich repeat 127..148 CDD:275381 4/20 (20%)
AMN1 144..>249 CDD:187754 25/140 (18%)
leucine-rich repeat 149..175 CDD:275381 5/25 (20%)
leucine-rich repeat 176..200 CDD:275381 5/24 (21%)
leucine-rich repeat 201..226 CDD:275381 8/59 (14%)
leucine-rich repeat 227..252 CDD:275381 7/24 (29%)
leucine-rich repeat 253..276 CDD:275381 5/22 (23%)
leucine-rich repeat 277..306 CDD:275381 6/33 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X5688
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.810

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