DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and Fbxl21

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	XP_038951543.1	Gene:	Fbxl21 / 306750	RGDID:	1305555	Length:	460	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	59/299 - (19%)
Similarity:	109/299 - (36%)	Gaps:	76/299 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWK--NVSLRPEVSGLHVGSLEMLLQLIS 99
            ||..|:|.||.||...:..|.:.:||.|.::.:...||:  ...|....:.....:...|:|.|.
  Rat    71 LPHHVILRIFQYLPLVDRARASSVCRSWNEVFHIPDLWRKFEFELNQSATSYFKSTHPDLIQQII 135

  Fly   100 VRFGPTLRYIELPIELITHTVLHELSAKCPNLTHMLLDFSTAMQLHDFSEMQAFPTKLRYMCVCL 164
            .:....|:|:...::..|.:.    .|.|..|:.::......:.|                 :..
  Rat   136 KKHAAHLQYVSFKVDSSTESA----EAACHILSQLVNCSIQTLGL-----------------IST 179

  Fly   165 SEVIFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIYEVINVHKLKSATPNLRVINLYGINF 229
            ::..||.  |.|.: |::.|.|:                  .:|...|.|..
  Rat   180 AKPSFMN--MPKSH-FVSALTVV------------------FVNSKSLSSIK------------- 210

  Fly   230 IDDSHID------AFSSNCIQLECLAVNFCNKVTGSTLKTLIQRSKRLTCLLMNGTSLKSEFVMQ 288
            |:|:.:|      ..::|...|..|.::.|..|:...:..:....:.|..|.:|...|..|.::
  Rat   211 IEDTPVDDPSLKILVANNSDTLRLLKMSSCPHVSSDGILCVADHCQGLRELALNYYILSDELLL- 274

  Fly   289 AEWDKCALQELDITATDLSTECL-VDMLSRIP-SLKFLS 325
                  ||.    :.|.::.|.| :|::|..| .:||.|
  Rat   275 ------ALS----SETHVNLEHLRIDVVSENPGQIKFHS 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	14/44 (32%)
		leucine-rich repeat	131..156	CDD:275381	2/24 (8%)
		leucine-rich repeat	157..175	CDD:275381	2/17 (12%)
		leucine-rich repeat	219..244	CDD:275381	4/30 (13%)
		leucine-rich repeat	245..270	CDD:275381	4/24 (17%)
		leucine-rich repeat	271..295	CDD:275381	5/23 (22%)
		leucine-rich repeat	296..320	CDD:275381	7/25 (28%)
		leucine-rich repeat	321..348	CDD:275381	3/5 (60%)
		leucine-rich repeat	349..375	CDD:275381
		leucine-rich repeat	376..403	CDD:275381
		leucine-rich repeat	405..432	CDD:275381
Fbxl21	XP_038951543.1	F-box-like	68..111	CDD:403981	14/39 (36%)
		leucine-rich repeat	206..231	CDD:275381	6/37 (16%)
		leucine-rich repeat	232..257	CDD:275381	4/24 (17%)
		leucine-rich repeat	258..283	CDD:275381	8/35 (23%)
		leucine-rich repeat	284..318	CDD:275381	8/20 (40%)
		leucine-rich repeat	329..365	CDD:275381
		AMN1	<359..>424	CDD:187754
		leucine-rich repeat	366..392	CDD:275381
		leucine-rich repeat	393..418	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346657
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750