DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and Fbxl3

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001094038.1	Gene:	Fbxl3 / 306129	RGDID:	1305660	Length:	428	Species:	Rattus norvegicus

Alignment Length:	317	Identity:	60/317 - (18%)
Similarity:	112/317 - (35%)	Gaps:	86/317 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DGTVRSPFADTTIEK---------LPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNV 77
            :||...|....|..:         |...::||:|.||...:....:::||.|.|:.:...||:..
  Rat    15 EGTAEKPKKPRTTHECSQPCDWGNLLQDIVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCF 79

  Fly    78 SL---RPEVSGLHVGSLEMLLQLISVRFGPTLRYIELPIELITHTVLHELSAKCPNLTHMLLDFS 139
            ..   :|..|.|.....|::.|:|. |....|:|:...::    :......|.|..|:.::....
  Rat    80 EFELNQPATSYLKATHPELIKQIIK-RHSNHLQYVSFKVD----SSKESAEAACDILSQLVNCSL 139

  Fly   140 TAMQLHDFSEMQAFPTKLRYMCVCLSEVIFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIY 204
            ..:.|                 :..:...||:  :.|.: ||:.|.|:
  Rat   140 KTLGL-----------------ISTARPSFMD--LPKSH-FISALTVV----------------- 167

  Fly   205 EVINVHKLKSATPNLRVINLYGINFIDDSHID------AFSSNCIQLECLAVNFCNKVTGSTLKT 263
             .:|...|.|..             |||:.:|      ..::|...|:.|.::.|..|:.:.:..
  Rat   168 -FVNSKSLSSLK-------------IDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILC 218

  Fly   264 LIQRSKRLTCLLMNGTSLKSEFVMQAEWDK-CALQELDITATDLSTECLVDMLSRIP 319
            :..:...|..|.:|...|..|.::....:| ..|:.|.|           |::|..|
  Rat   219 VADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRI-----------DVVSENP 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	12/57 (21%)
		leucine-rich repeat	131..156	CDD:275381	2/24 (8%)
		leucine-rich repeat	157..175	CDD:275381	2/17 (12%)
		leucine-rich repeat	219..244	CDD:275381	5/30 (17%)
		leucine-rich repeat	245..270	CDD:275381	4/24 (17%)
		leucine-rich repeat	271..295	CDD:275381	6/24 (25%)
		leucine-rich repeat	296..320	CDD:275381	6/24 (25%)
		leucine-rich repeat	321..348	CDD:275381
		leucine-rich repeat	349..375	CDD:275381
		leucine-rich repeat	376..403	CDD:275381
		leucine-rich repeat	405..432	CDD:275381
Fbxl3	NP_001094038.1	F-box-like	36..77	CDD:403981	11/40 (28%)
		leucine-rich repeat	174..199	CDD:275381	7/37 (19%)
		leucine-rich repeat	200..225	CDD:275381	4/24 (17%)
		leucine-rich repeat	252..286	CDD:275381	6/24 (25%)
		leucine-rich repeat	287..333	CDD:275381
		leucine-rich repeat	334..360	CDD:275381
		leucine-rich repeat	361..383	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346632
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940