DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FipoQ and Amn1

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001008334.2	Gene:	Amn1 / 302032	RGDID:	1308119	Length:	258	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	63/308 - (20%)
Similarity:	114/308 - (37%)	Gaps:	77/308 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SHREICRLARICRRWRQIAYDTRLWKNVS--------LRPEVSGLHVGSLEMLLQLISVRFGPTL 106
            |.|.:.:|..:|.|...|        |:|        |.|.:.       :.|::::|:|.
  Rat     3 SSRVVSQLLELCLRCLII--------NISRYISDIKYLPPNIK-------DRLIKIMSMRG---- 48

  Fly   107 RYIELPIELITHTVLHELSAKCPNLTHMLLDFSTAMQLHDFSEMQAFPTKLRYMCVCLSEVIFME 171
            |..:..|..:.|..:..|..:..|::.:                     .|:::|.|
  Rat    49 RITDSNINEVLHPEVQRLDLRSCNISDV---------------------ALQHLCKC-------- 84

  Fly   172 GFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIYEVINVHKLKSATPNLRVINLYGINFIDDSHID 236
               ||       |:.|:|    :.|.|....|... .:..:.|:..:|..|:|.|...:.|..:.
  Rat    85 ---RK-------LKALNL----KSCREHRNSITSE-GIKAVASSCSDLHEISLKGCCSVTDEGVL 134

  Fly   237 AFSSNCIQLECLAVNFCNKVTGSTLKTLIQRSKRLTCLLMNGTSLKSEFVMQAEWDKCA--LQEL 299
            |.:.||..|:.:.:..|..:|..:|..|.:....|.|:..:.|.:....|:......||  |:|:
  Rat   135 ALALNCQLLKIIDLGGCLSITDESLHALGKNCPFLQCVDFSTTQVSDNGVVALVSGPCAKQLEEI 199

  Fly   300 D----ITATDLSTECLVDMLSRIPSLKFLSAGQINGFNDSVLKQWMES 343
            :    |..||.:.|..:....:|..|.|.....|...:..||:|.:.|
  Rat   200 NMGYCINLTDKAVEAALTACPQICILLFHGCPLITDHSREVLEQLIGS 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	8/37 (22%)
		leucine-rich repeat	131..156	CDD:275381	0/24 (0%)
		leucine-rich repeat	157..175	CDD:275381	3/17 (18%)
		leucine-rich repeat	219..244	CDD:275381	8/24 (33%)
		leucine-rich repeat	245..270	CDD:275381	5/24 (21%)
		leucine-rich repeat	271..295	CDD:275381	4/23 (17%)
		leucine-rich repeat	296..320	CDD:275381	7/27 (26%)
		leucine-rich repeat	321..348	CDD:275381	7/23 (30%)
		leucine-rich repeat	349..375	CDD:275381
		leucine-rich repeat	376..403	CDD:275381
		leucine-rich repeat	405..432	CDD:275381
Amn1	NP_001008334.2	leucine-rich repeat	10..35	CDD:275381	7/32 (22%)
		leucine-rich repeat	36..58	CDD:275381	5/32 (16%)
		AMN1	37..257	CDD:187754	53/266 (20%)
		leucine-rich repeat	63..86	CDD:275381	5/54 (9%)
		leucine-rich repeat	87..116	CDD:275381	7/33 (21%)
		leucine-rich repeat	117..142	CDD:275381	8/24 (33%)
		leucine-rich repeat	143..168	CDD:275381	5/24 (21%)
		leucine-rich repeat	169..195	CDD:275381	6/25 (24%)
		leucine-rich repeat	196..221	CDD:275381	6/24 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900