DRSC/TRiP Functional Genomics Resources

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Protein Alignment FipoQ and Fbxl4

DIOPT Version :9

Sequence 1:NP_733291.1 Gene:FipoQ / 43475 FlyBaseID:FBgn0039667 Length:515 Species:Drosophila melanogaster
Sequence 2:NP_766576.1 Gene:Fbxl4 / 269514 MGIID:2140367 Length:621 Species:Mus musculus


Alignment Length:392 Identity:95/392 - (24%)
Similarity:155/392 - (39%) Gaps:93/392 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 SQVYLSDGTVRSPFADTTIEKLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVSLR 80
            |...|.||.....|     :|||.:::..|.::||..::||||:.||...|...|...:.:::|:
Mouse   267 SSAALGDGPHNGYF-----DKLPYELIQLILNHLSLPDLCRLAQTCRLLHQHCCDPLQYIHLNLQ 326

  Fly    81 PEVSGLHVGSLEML---------LQL--------ISV----RF----GPTLRYIELPI-ELITHT 119
            |..:.|...|||.|         |.|        |||    ||    |..|..:||.. ..:..|
Mouse   327 PYWARLDDTSLEFLQARCVLVQWLNLSWTGNRGFISVSGFSRFLKVCGSELVRLELSCSHFLNDT 391

  Fly   120 VLHELSAKCPNLTHMLLD---------FSTAMQLHDFSEMQAFPTKLRYMCVCLSEVIFMEGFMR 175
            .|..:|..||||..:.|.         |....:|.....:..:.||:.            :..:.
Mouse   392 CLEVISEMCPNLQDLNLSSCDKLPPQAFGHIAKLCSLKRLVLYRTKVE------------QTALL 444

  Fly   176 KIYNFINGLEVLHL-IGTYEKCEEEEEEIYEVINVHKLKSATPNLRVINLYGINFIDDSHIDAFS 239
            .|.||.  .|:.|| :|:....|:     |:|| ...:.:...|||.::|:....|.::.|...:
Mouse   445 SILNFC--AELQHLSLGSCVMIED-----YDVI-ASMIGAKCKNLRTLDLWRCKNITENGIAELA 501

  Fly   240 SNCIQLECLAVNFCNKVTGSTLKTLIQRSKRLTCLLMNGTSLKSEFVMQAEWDKCALQELDITAT 304
            |.|:.||.|.:.:|..:..||           .|.:.....|.:            ||:|.:||.
Mouse   502 SGCVLLEELDLGWCPTLQSST-----------GCFVRLARQLPN------------LQKLFLTAN 543

  Fly   305 ----DLSTECLVDMLSRIPSLKFLSAGQINGFNDSVLKQWMESGTTRSLISLDLDSSDNISDEGL 365
                |...|.|....:|:..|..|....:   :.:.|::.:||  .:.|..||:.....|.::.:
Mouse   544 RSVCDTDIEELASNCTRLQQLDILGTRMV---SPASLRKLLES--CKDLSLLDVSFCSQIDNKAV 603

  Fly   366 LK 367
            |:
Mouse   604 LE 605

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FipoQNP_733291.1 F-box-like 34..80 CDD:289689 14/45 (31%)
leucine-rich repeat 131..156 CDD:275381 4/33 (12%)
leucine-rich repeat 157..175 CDD:275381 0/17 (0%)
leucine-rich repeat 219..244 CDD:275381 7/24 (29%)
leucine-rich repeat 245..270 CDD:275381 6/24 (25%)
leucine-rich repeat 271..295 CDD:275381 2/23 (9%)
leucine-rich repeat 296..320 CDD:275381 9/27 (33%)
leucine-rich repeat 321..348 CDD:275381 5/26 (19%)
leucine-rich repeat 349..375 CDD:275381 5/19 (26%)
leucine-rich repeat 376..403 CDD:275381
leucine-rich repeat 405..432 CDD:275381
Fbxl4NP_766576.1 F-box-like 280..318 CDD:372399 15/42 (36%)
leucine-rich repeat 295..317 CDD:275381 9/21 (43%)
leucine-rich repeat 318..340 CDD:275381 6/21 (29%)
leucine-rich repeat 347..376 CDD:275381 8/28 (29%)
LRR 1 376..397 5/20 (25%)
leucine-rich repeat 377..402 CDD:275381 7/24 (29%)
AMN1 394..601 CDD:187754 55/254 (22%)
LRR 2 402..421 4/18 (22%)
leucine-rich repeat 403..427 CDD:275381 4/23 (17%)
LRR 3 427..448 3/32 (9%)
leucine-rich repeat 428..452 CDD:275381 5/37 (14%)
LRR 4 452..474 8/27 (30%)
leucine-rich repeat 453..480 CDD:275381 7/32 (22%)
LRR 5 480..501 6/20 (30%)
leucine-rich repeat 481..506 CDD:275381 7/24 (29%)
LRR 6 504..524 7/30 (23%)
leucine-rich repeat 507..534 CDD:275381 8/37 (22%)
LRR 7 532..558 9/37 (24%)
leucine-rich repeat 535..560 CDD:275381 8/24 (33%)
LRR 8 559..583 4/26 (15%)
leucine-rich repeat 561..586 CDD:275381 5/29 (17%)
LRR 9 584..609 5/22 (23%)
leucine-rich repeat 587..612 CDD:275381 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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