DRSC/TRiP Functional Genomics Resources

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Protein Alignment FipoQ and FBXL3

DIOPT Version :9

Sequence 1:NP_733291.1 Gene:FipoQ / 43475 FlyBaseID:FBgn0039667 Length:515 Species:Drosophila melanogaster
Sequence 2:NP_036290.1 Gene:FBXL3 / 26224 HGNCID:13599 Length:428 Species:Homo sapiens


Alignment Length:317 Identity:61/317 - (19%)
Similarity:113/317 - (35%) Gaps:86/317 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 DGTV-RSPFADTTIE--------KLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNV 77
            :||. :|....||.|        .|...::|.:|.||...:....:::||.|.|:.:...||:..
Human    15 EGTAEKSKKLRTTNEHSQTCDWGNLLQDIILQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCF 79

  Fly    78 SL---RPEVSGLHVGSLEMLLQLISVRFGPTLRYIELPIELITHTVLHELSAKCPNLTHMLLDFS 139
            ..   :|..|.|.....|::.|:|. |....|:|:...::    :......|.|..|:.::....
Human    80 EFELNQPATSYLKATHPELIKQIIK-RHSNHLQYVSFKVD----SSKESAEAACDILSQLVNCSL 139

  Fly   140 TAMQLHDFSEMQAFPTKLRYMCVCLSEVIFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIY 204
            ..:.|                 :..:...||:  :.|.: ||:.|.|:                 
Human   140 KTLGL-----------------ISTARPSFMD--LPKSH-FISALTVV----------------- 167

  Fly   205 EVINVHKLKSATPNLRVINLYGINFIDDSHID------AFSSNCIQLECLAVNFCNKVTGSTLKT 263
             .:|...|.|..             |||:.:|      ..::|...|:.|.::.|..|:.:.:..
Human   168 -FVNSKSLSSLK-------------IDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILC 218

  Fly   264 LIQRSKRLTCLLMNGTSLKSEFVMQAEWDK-CALQELDITATDLSTECLVDMLSRIP 319
            :..:...|..|.:|...|..|.::....:| ..|:.|.|           |::|..|
Human   219 VADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRI-----------DVVSENP 264

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FipoQNP_733291.1 F-box-like 34..80 CDD:289689 12/56 (21%)
leucine-rich repeat 131..156 CDD:275381 2/24 (8%)
leucine-rich repeat 157..175 CDD:275381 2/17 (12%)
leucine-rich repeat 219..244 CDD:275381 5/30 (17%)
leucine-rich repeat 245..270 CDD:275381 4/24 (17%)
leucine-rich repeat 271..295 CDD:275381 6/24 (25%)
leucine-rich repeat 296..320 CDD:275381 6/24 (25%)
leucine-rich repeat 321..348 CDD:275381
leucine-rich repeat 349..375 CDD:275381
leucine-rich repeat 376..403 CDD:275381
leucine-rich repeat 405..432 CDD:275381
FBXL3NP_036290.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..27 3/11 (27%)
F-box-like 36..77 CDD:403981 10/40 (25%)
LRR 1 119..146 4/43 (9%)
leucine-rich repeat 174..199 CDD:275381 7/37 (19%)
LRR 2 181..207 5/25 (20%)
leucine-rich repeat 200..225 CDD:275381 4/24 (17%)
LRR 3 208..233 4/24 (17%)
LRR 4 234..259 6/35 (17%)
leucine-rich repeat 252..286 CDD:275381 6/24 (25%)
leucine-rich repeat 287..333 CDD:275381
LRR 5 316..341
leucine-rich repeat 334..360 CDD:275381
LRR 6 343..368
leucine-rich repeat 361..383 CDD:275381
LRR 7 369..394
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165153032
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1027299at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.840

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