DRSC/TRiP Functional Genomics Resources

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Protein Alignment FipoQ and Fbxl16

DIOPT Version :9

Sequence 1:NP_733291.1 Gene:FipoQ / 43475 FlyBaseID:FBgn0039667 Length:515 Species:Drosophila melanogaster
Sequence 2:NP_001366323.1 Gene:Fbxl16 / 214931 MGIID:2448488 Length:575 Species:Mus musculus


Alignment Length:523 Identity:97/523 - (18%)
Similarity:182/523 - (34%) Gaps:182/523 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 LAVEASQVYL-------SDGTVRSPFADTTIEKLP----DKVLLHIFSYLSHREICRLARICRRW 64
            ||...|:|.|       :.|....|.:...:|:.|    :|:|..:|.|.|..|.|.||::|:.|
Mouse   156 LATPLSRVALAGGPCPPASGPASGPVSGPPVERPPLATDEKILNGLFWYFSACEKCILAQVCKAW 220

  Fly    65 RQIAYDTRLWKNVSLRPEVSGLHVGSLEMLLQLISVRFGPTLRYIELPIELITHTVLHELSAKCP 129
            |::.|..:.|  ..|.|                                      |||       
Mouse   221 RRVLYQPKFW--AGLTP--------------------------------------VLH------- 238

  Fly   130 NLTHMLLDFSTAMQLHDFSEMQAFPTKLRYMCVCLSEVIFMEGFMRKIYNFINGLEVLHLIGT-- 192
                       |.:|::     ..|...:       |.:.::||..:      |.|...|:|.  
Mouse   239 -----------AKELYN-----VLPGGEK-------EFVNLQGFAAR------GFEGFCLVGVSD 274

  Fly   193 YEKCEEEEEEIYEVINVHKLKSATPNLRVINLYGINFIDDSHIDAFSSNCIQLECLAVNFCNKVT 257
            .:.||                               |||:..:.......:.|:      .:.:|
Mouse   275 LDICE-------------------------------FIDNYSLSKKGVKAMSLK------RSTIT 302

  Fly   258 GSTLKTLIQRSKRLTCLLMNGTSLKSEFVMQAEWDKCALQELDITATD---LSTECLVDMLSRIP 319
            .:.|:.::::.:.:..|.::|.   ::|.....|...:.:...::.:|   ::.:.:..:...:|
Mouse   303 DAGLEVMLEQMQGVVRLELSGC---NDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLP 364

  Fly   320 SLKFLSAGQINGFNDSVLKQWMESGTTRSLISLDLDSSDNISDEGLLKFIQRQGHQLSACCLSGM 384
            :|..||.                             .:.:::|..|..|..||||......|...
Mouse   365 NLAELSL-----------------------------QAYHVTDTALAYFTARQGHSTHTLRLLSC 400

  Fly   385 PHITDQLWMSILPLLGNCKIIVMGTAEKLGVNIHVDQLMDTIASNCGNLERLELRWDPDNLRFSD 449
            ..||:...::::..|.|...:.:....|:     .|..::.:|.|...|..|:|.|.|   |.:|
Mouse   401 WEITNHGVVNVVHSLPNLTSLSLSGCSKV-----TDDGVELVAENLRKLRSLDLSWCP---RITD 457

  Fly   450 KSQK--AIDILRVKCLKL-RCMVLSD-GRYYETVKANFERADRITVVRTTTCCRVSPY---HLLR 507
            .:.:  |.|:.|::.|.| ||:.::| |..|.:..::.    |...:|  .||:|..:   |||.
Mouse   458 MALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSL----RSLYLR--WCCQVQDFGLKHLLA 516

  Fly   508 NYN 510
            ..|
Mouse   517 MRN 519

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FipoQNP_733291.1 F-box-like 34..80 CDD:289689 16/49 (33%)
leucine-rich repeat 131..156 CDD:275381 3/24 (13%)
leucine-rich repeat 157..175 CDD:275381 3/17 (18%)
leucine-rich repeat 219..244 CDD:275381 3/24 (13%)
leucine-rich repeat 245..270 CDD:275381 3/24 (13%)
leucine-rich repeat 271..295 CDD:275381 4/23 (17%)
leucine-rich repeat 296..320 CDD:275381 1/26 (4%)
leucine-rich repeat 321..348 CDD:275381 3/26 (12%)
leucine-rich repeat 349..375 CDD:275381 6/25 (24%)
leucine-rich repeat 376..403 CDD:275381 5/26 (19%)
leucine-rich repeat 405..432 CDD:275381 4/26 (15%)
Fbxl16NP_001366323.1 PHA03247 <31..193 CDD:223021 9/36 (25%)
AMN1 297..509 CDD:187754 49/263 (19%)
leucine-rich repeat 316..339 CDD:275381 4/25 (16%)
leucine-rich repeat 340..365 CDD:275381 1/24 (4%)
leucine-rich repeat 366..391 CDD:275381 9/53 (17%)
leucine-rich repeat 392..417 CDD:275381 4/24 (17%)
leucine-rich repeat 418..443 CDD:275381 4/29 (14%)
leucine-rich repeat 444..469 CDD:275381 9/27 (33%)
leucine-rich repeat 470..494 CDD:275381 7/23 (30%)
leucine-rich repeat 495..514 CDD:275381 5/24 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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