DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and Fbxl21

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001333661.1	Gene:	Fbxl21 / 213311	MGIID:	2442921	Length:	460	Species:	Mus musculus

Alignment Length:	341	Identity:	71/341 - (20%)
Similarity:	119/341 - (34%)	Gaps:	107/341 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ASQVYLSDGTVRSPFADTTIEKLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWK--NV 77
            |..|.|..||            ||..|:|.||.||...:..|.:.:||||.::.:...||:  ..
Mouse    61 ALSVLLDWGT------------LPHHVILQIFQYLPLIDRARASSVCRRWNEVFHIPDLWRKFEF 113

  Fly    78 SLRPEVSGLHVGSLEMLLQLISVRFGPTLRYIELPIELITHT------VLHELSAKCPNLTHMLL 136
            .|....:.....:...|:|.|..:....|:|:...::..|.:      :|.:| ..|...|..|:
Mouse   114 ELNQSATSYFKSTHPDLIQQIIKKHAAHLQYVSFKVDSSTESAEAACDILSQL-VNCSIQTLGLI 177

  Fly   137 DFSTAMQLHDFSEMQAFPTKLRYMCVCLSEVIFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEE 201
              |||              |..:|.|..|             :|::.|.|:
Mouse   178 --STA--------------KPSFMNVPKS-------------HFVSALTVV-------------- 199

  Fly   202 EIYEVINVHKLKSATPNLRVINLYGINFIDDSHID------AFSSNCIQLECLAVNFCNKVTGST 260
                .:|...|.|..             |:|:.:|      ..::|...|..|.::.|..|:...
Mouse   200 ----FVNSKSLSSIK-------------IEDTPVDDPSLKILVANNSDTLRLLKMSSCPHVSSDG 247

  Fly   261 LKTLIQRSKRLTCLLMNGTSLKSEFVMQAEWDKCALQELDITATDLSTECL-VDMLSRIPSLKFL 324
            :..:....:.|..|.:|...|..|.::       ||.    :.|.::.|.| :|::|..|
Mouse   248 ILCVADHCQGLRELALNYYILSDEILL-------ALS----SETHVNLEHLRIDVVSENP----- 296

  Fly   325 SAGQINGFNDSVLKQW 340
              |||. |:....:.|
Mouse   297 --GQIK-FHSIKKRSW 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	15/47 (32%)
		leucine-rich repeat	131..156	CDD:275381	5/24 (21%)
		leucine-rich repeat	157..175	CDD:275381	3/17 (18%)
		leucine-rich repeat	219..244	CDD:275381	4/30 (13%)
		leucine-rich repeat	245..270	CDD:275381	4/24 (17%)
		leucine-rich repeat	271..295	CDD:275381	5/23 (22%)
		leucine-rich repeat	296..320	CDD:275381	6/24 (25%)
		leucine-rich repeat	321..348	CDD:275381	5/20 (25%)
		leucine-rich repeat	349..375	CDD:275381
		leucine-rich repeat	376..403	CDD:275381
		leucine-rich repeat	405..432	CDD:275381
Fbxl21	NP_001333661.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843151
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750