DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FipoQ and fbxl4

DIOPT Version :9

Sequence 1:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	XP_031761765.1	Gene:	fbxl4 / 100490265	XenbaseID:	XB-GENE-961513	Length:	622	Species:	Xenopus tropicalis

Alignment Length:	397	Identity:	88/397 - (22%)
Similarity:	154/397 - (38%)	Gaps:	114/397 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LSDGTVRSPFADTTIEKLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVSLRPEVS 84
            ||:..:|....:...:|||.:::..|.|:|:..::||||:.|:...|...|...:.::||:|..:
Frog   267 LSNTGIREWTNNGYFDKLPYELIQFIISHLALPDLCRLAQTCKLMYQHCCDPLQYTHLSLQPYWT 331

  Fly    85 GLHVGSLEMLL--------------------------QLISVRFGPTLRYIELPI-ELITHTVLH 122
            .::..|||.||                          :|:.| .|..|..:||.. ..:....|.
Frog   332 NVNDNSLEYLLPRCSLVQWLNLSWTGNRGLISTSGFSRLLKV-CGSELVRLELACGHFLNEACLE 395

  Fly   123 ELSAKCPNLTHMLLDFSTAMQLHDFSEMQAFPTKLRYMCVCLSEVIFMEGFMRKIYNFINGLEVL 187
            .::..||||..  |:.|:..:|.        |....::|.                  ::||:.|
Frog   396 VIAEMCPNLQE--LNLSSCDKLP--------PQAFSHICK------------------LSGLKRL 432

  Fly   188 HLIGTYEKCEEEEEEIYEVINVHKLKSATPNLRVINLYGINFIDDSHIDA--FSSNCIQLECLAV 250
            .|..|    :.|:..:..::|.      .|.::.:||.....|:|..:.|  ..:.|.:|..|.:
Frog   433 VLYRT----KIEQTALLSILNF------CPEIQHLNLGSCVLIEDYDLVASVLGAKCKKLRSLDL 487

  Fly   251 NFCNKVTGSTLKTLIQRSKRLTCLLMNGTSLKSEFVMQAEWDKCALQELDI---TATDLSTECLV 312
            ..|..:|...:..|..     .|||                    |:|||:   .....||.|.|
Frog   488 WRCKNITERGIAELAS-----GCLL--------------------LEELDLGWCPTLQSSTGCFV 527

  Fly   313 DMLSRIPSLK--FLSAGQINGFNDSVLKQWME--SGTTRSLISLDLDSSDNISDEGLLKFIQRQG 373
            ::.|::|:|:  ||:|      |.||....:|  :...:.|..||:..:..:|...|.|.::
Frog   528 NLASKLPNLRKLFLTA------NRSVCDSDIEELARNCQHLQQLDILGTRMVSPAALCKLLE--- 583

  Fly   374 HQLSACC 380
                 ||
Frog   584 -----CC 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	14/45 (31%)
		leucine-rich repeat	131..156	CDD:275381	5/24 (21%)
		leucine-rich repeat	157..175	CDD:275381	1/17 (6%)
		leucine-rich repeat	219..244	CDD:275381	6/26 (23%)
		leucine-rich repeat	245..270	CDD:275381	5/24 (21%)
		leucine-rich repeat	271..295	CDD:275381	3/23 (13%)
		leucine-rich repeat	296..320	CDD:275381	9/26 (35%)
		leucine-rich repeat	321..348	CDD:275381	8/30 (27%)
		leucine-rich repeat	349..375	CDD:275381	6/25 (24%)
		leucine-rich repeat	376..403	CDD:275381	2/5 (40%)
		leucine-rich repeat	405..432	CDD:275381
fbxl4	XP_031761765.1	F-box-like	281..325	CDD:403981	13/43 (30%)
		leucine-rich repeat	296..318	CDD:275381	7/21 (33%)
		leucine-rich repeat	319..341	CDD:275381	6/21 (29%)
		leucine-rich repeat	348..377	CDD:275381	3/29 (10%)
		leucine-rich repeat	378..403	CDD:275381	5/24 (21%)
		leucine-rich repeat	404..428	CDD:275381	6/51 (12%)
		AMN1	427..606	CDD:187754	48/208 (23%)
		leucine-rich repeat	429..453	CDD:275381	6/33 (18%)
		leucine-rich repeat	454..481	CDD:275381	6/26 (23%)
		leucine-rich repeat	482..507	CDD:275381	6/29 (21%)
		leucine-rich repeat	508..535	CDD:275381	9/26 (35%)
		leucine-rich repeat	536..561	CDD:275381	8/30 (27%)
		leucine-rich repeat	562..587	CDD:275381	8/32 (25%)
		leucine-rich repeat	588..613	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910