DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2006 and Y53C12A.10

DIOPT Version :9

Sequence 1:	NP_001189310.1	Gene:	CG2006 / 43472	FlyBaseID:	FBgn0039664	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_001254222.1	Gene:	Y53C12A.10 / 13186571	WormBaseID:	WBGene00175030	Length:	235	Species:	Caenorhabditis elegans

Alignment Length:	297	Identity:	81/297 - (27%)
Similarity:	130/297 - (43%)	Gaps:	100/297 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 IADH----SALDTIEG--RHNCRLCNRSRKFFCYSCCVPVGELEELLPRLELPLQVDIIKHKKEI 79
            |::|    |:.|.||.  :..|..|..:||:|||.|..|:..:  ..|.::||..|||:||..|.
Worm     4 ISEHQVQLSSFDPIENCVKSTCPGCKSNRKYFCYDCRTPMPGV--FTPTVKLPCAVDIVKHPMEK 66

  Fly    80 DGKSSAVHAAVLAPAHVRIHTFPDIPDYREEA-----GVVLIFPSATALAVPQLFARNVQLQIGD 139
            :.||||:|..::||...|:..:|::.||.:::     |..:||||.:|::|.: |.:.
Worm    67 NSKSSALHCKIVAPDQTRVFDYPNVHDYSQDSEDERQGTAIIFPSKSAISVEE-FVKT------- 123

  Fly   140 NYGLPKGHHMGTMLRRRMDEVEVKELQEEVDEPETVRRTWTLDNLPVRRAVFIDSTWNQSRGIYA 204
                 :|                                      |::|.|.:|.||.|...:..
Worm   124 -----RG--------------------------------------PIKRIVVLDCTWFQVGVMQK 145

  Fly   205 DARVRGLRTVVLQNRLSQFWRHQRGSPRWYLATIEAIHQFLLEVHINAWGLNTAYRGLDNLEITA 269
            ..:::||:.|.||:..:.|||.|...|...|||||||:..|.|           |:.|
Worm   146 TPQIQGLQHVSLQSYRTAFWRPQHNVPETGLATIEAIYYSLRE-----------YQEL------- 192

  Fly   270 GFHQLAEPLTKTAASENVGREAPYNGQYDNLLFFFAH 306
                            .:||:  |:|::|:||::|.|
Worm   193 ----------------GLGRK--YSGEFDDLLYWFFH 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2006	NP_001189310.1	DTW	44..312	CDD:281875	72/268 (27%)
Y53C12A.10	NP_001254222.1	DTW	33..209	CDD:377168	70/264 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167520
Domainoid	1	1.000	85	1.000	Domainoid score	I5244
eggNOG	1	0.900	-	-		E1_KOG3795
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10633
Inparanoid	1	1.050	97	1.000	Inparanoid score	I3613
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54886
OrthoDB	1	1.010	-	-		D601886at33208
OrthoFinder	1	1.000	-	-		FOG0006376
OrthoInspector	1	1.000	-	-		oto20761
orthoMCL	1	0.900	-	-		OOG6_104689
Panther	1	1.100	-	-	LDO	PTHR15627
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3038
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800