Protein Alignment Ptp99A and Ptprr

DIOPT Version :10

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_063120425.1
• Gene: Ptprr / 94202
• RGDID: 620780
• Length: 684
• Species: Rattus norvegicus
• Alignment Length: 766
• Identity: 191/766 - (24%)
• Similarity: 308/766 - (40%)
• Gaps: 209/766 - (27%)

  Fly   228 SKESYYIVTLREAPTGKPIPTTAHNTS-STSVYISWKA-----PPPDTILGEFLGYRITYR---- 282
            |:.:.:.:.:|:..:.||:....|:.. ..|:.|:.:|     |.|..:       :|:.|
  Rat    51 SRNNDHFLAIRQKKSWKPMFIYDHSQDIKKSLDIAQEAYKHNYPAPSEV-------QISKRHQIV 108

  Fly   283 ----PRDR-DPNDTKEIYIRDNTVESHEIQNLQTYTQYKVTVQVFNPEGLGPETTILVMTDEGVP 342
                ||.. ||:    :.:...:.:..||:||..                 |...::|:|.: :.
  Rat   109 DSAFPRPAYDPS----LNLLAASGQDLEIENLPI-----------------PAANVIVVTLQ-MD 151

  Fly   343 SKPQNLTILDVSANSITMSWHPPKNQNGAIAGYHVFHIHDNQTGVEIVKNSRNSVETLIHFELQN 407
            ....|:|:|.:....:           .|..|.....:|.|:.   |.|.|:  :|..:  ...|
  Rat   152 IDKLNITLLRIFRQGV-----------AAALGLLPQQVHINRL---IEKKSQ--IELFV--SPGN 198

  Fly   408 LRPYTDYRVIVKAFTTKNEGEPSDQIAQ------RTDVGGPSAP--AIVNLT--------CHSQE 456
            .:|                |||....|:      ..||...|.|  .|::::        .|..:
  Rat   199 RKP----------------GEPQALQAEEVLRSLNVDVLRQSLPQFGIIDVSPEKNVLQGQHEAD 247

  Fly   457 SITIRWRRPYEFYNTIDF--------------YIIKTRL---AGQDTHRDIRINASAKELETAMI 504
            .|   |.:. .||..:.|              |.:|.||   ..||..::..|:.|...|:.|.
  Rat   248 KI---WSKE-GFYAVVIFLSIFIIIVTCLMIIYRLKERLQLSLRQDKEKNQEIHLSPIALQQAQ- 307

  Fly   505 LQNLTTNSYYEVKVAAATFS----------VINPKKIVLGKFSESRIIQLQPNCEKLQPLLRQSH 559
                     .|.|.|.:...          |::|:.....:...:....:.|:..:::|:..|..
  Rat   308 ---------SEAKAAHSMVQPDQAPKVLNVVVDPQGQCTPEIRNTASTSVCPSPFRMKPIGLQER 363

  Fly   560 NDYNLAVLVGIIFSCFGIILIIMAFFLWSRKCFHAAYYYLDDPPHHPNAPQVDWEVPVKIGDEIR 624
            ...|:::.:.:  |..|.:...:|......|   .|..||.........||:
  Rat   364 RGSNVSLTLDM--SSLGNVEPFVAVSTPREK---VAMEYLQSASRVLTRPQL------------- 410

  Fly   625 AAVPVNEFAKHVASLHADGDIGFSREYEAIQNECISDDLPC-----EHSQHPENKRKNRYLNITA 684
                    ...|||.|            .:|:|.:  ::|.     :....|.:..||||..|..
  Rat   411 --------RDVVASSH------------LLQSEFM--EIPMNFVDPKEIDIPRHGTKNRYKTILP 453

  Fly   685 YDHSRVHLHPTPGQKKNL-----DYINANFIDGYQ-KGHAFIGTQGPLPDTFDCFWRMIWEQRVA 743
            ...|||.|.|     ||:     .|||||:|.||. |..|||.||||:.:|.:.||:|:|::...
  Rat   454 NPLSRVCLRP-----KNITDPLSTYINANYIRGYSGKEKAFIATQGPMINTVNDFWQMVWQEDSP 513

  Fly   744 IIVMITNLVERGRRKCDMYWP-KDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNT 807
            :|||||.|.|: ..||.:||| |.|:  ||.::|.:|.......||:|.|.:       |:..:|
  Rat   514 VIVMITKLKEK-NEKCVLYWPEKRGI--YGKVEVLVIGVNECDNYTIRNLVL-------KRGSHT 568

  Fly   808 EKLVYQYHYTNWPDHGTPDHPLPVLNF---VKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAM 869
            :. |..|.||:||||.|||...|:|..   |::...|:... ||:|||||||:||||.:|.....
  Rat   569 QH-VKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASEGR-GPVVVHCSAGIGRTGCFIATSIG 631

  Fly   870 LKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDA--LVEAIASGET 918
            .:|::::.:|:....:..:|..|..:|||.|||.|:|.|  |.|:..|.||
  Rat   632 CQQLKEEGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHALCLFESRLSPET 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020	1/7 (14%)
		FN3	243..337	CDD:238020	20/108 (19%)
		fn3	343..430	CDD:394996	15/86 (17%)
		FN3	442..520	CDD:238020	21/104 (20%)
		R5-PTPc-1	704..907	CDD:350397	85/207 (41%)
		R5-PTP-2	989..1182	CDD:350398
Ptprr	XP_063120425.1	None