Protein Alignment Ptp99A and PTP1

DIOPT Version :10

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_010051.1
• Gene: PTP1 / 851368
• SGDID: S000002389
• Length: 335
• Species: Saccharomyces cerevisiae
• Alignment Length: 300
• Identity: 90/300 - (30%)
• Similarity: 136/300 - (45%)
• Gaps: 81/300 - (27%)

  Fly   668 SQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFIDGYQKGHA-----FIGTQGPLP 727
            |..|.|..:|||:||..|:.:||||....|.    |||||:::.....|.:     :|.||||..
Yeast    47 SIEPRNDARNRYVNIMPYERNRVHLKTLSGN----DYINASYVKVNVPGQSIEPGYYIATQGPTR 107

  Fly   728 DTFDCFWRMIWEQ---RVAIIVMITNLVERGRRKCDMYWPKDGVETYGVIQVKLIEEEVMSTYTV 789
            .|:|.||:|.:..   ...:|||:|.|||..|.||..|||:.||:.                 ||
Yeast   108 KTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDD-----------------TV 155

  Fly   790 R-------------------TLQIKHLKLKKKKQCNT---------------EKLVYQYHYTNWP 820
            |                   .|:|:.:.:.|.|...|               .|.|:.:::..|.
Yeast   156 RIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWK 220

  Fly   821 DHGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQ-IQQKNIVN---- 880
            |...|:..:|::.....|.:.| :...||:||||||||||||:|.||.::.. :..|||..
Yeast   221 DMNKPEEVVPIMELCAHSHSLN-SRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRH 284

  Fly   881 ------------VFGFLRHIRAQRNFLVQTEEQYIFLHDA 908
                        :...:..:|:||..:|||::|::|::.|
Yeast   285 SDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHA 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		FN3	243..337	CDD:238020
		fn3	343..430	CDD:394996
		FN3	442..520	CDD:238020
		R5-PTPc-1	704..907	CDD:350397	74/261 (28%)
		R5-PTP-2	989..1182	CDD:350398
PTP1	NP_010051.1	PTP_fungal	79..323	CDD:350509	74/261 (28%)