DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp99A and PTP1

DIOPT Version :9

Sequence 1:	NP_651691.4	Gene:	Ptp99A / 43469	FlyBaseID:	FBgn0004369	Length:	1397	Species:	Drosophila melanogaster
Sequence 2:	NP_001031266.1	Gene:	PTP1 / 843516	AraportID:	AT1G71860	Length:	340	Species:	Arabidopsis thaliana

Alignment Length:	247	Identity:	84/247 - (34%)
Similarity:	134/247 - (54%)	Gaps:	12/247 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   673 NKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFIDGYQKG--HAFIGTQGPLPDTFDCFWR 735
            |..||||.::..:|.:|:.|:|....... .|:||:.|...:..  ..||.||||||.|.:.||.
plant    87 NVEKNRYSDVVPFDKNRIVLNPCKDSSAK-GYVNASLIKTSESESISQFIATQGPLPHTMEDFWE 150

  Fly   736 MIWEQRVAIIVMITNLVERGRR-KC-DMYWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLK 798
            |:.:|...||||:|.||:..|. || |.:..:||...:|  .:.|..:.:.:|.|  :|.:::|:
plant   151 MVIQQHCPIIVMLTRLVDNNRTVKCGDYFQDEDGPREFG--NISLTTKWIKTTDT--SLMLRNLE 211

  Fly   799 LKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTY 863
            :..|:..:....|....|..|||||.|...:.|...:|:.... |...|||:||||||:||||||
plant   212 VNYKETEDQPMSVLHIQYPEWPDHGVPKDTVAVREILKRLYQV-PPSLGPIIVHCSAGIGRTGTY 275

  Fly   864 IVLDAMLKQI--QQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI 913
            ..:...:::|  ...:.:::...:...|.||..:|||.:||.|.::|:|:.:
plant   276 CAIHNTIQRILAGDMSALDLAKTVALFRKQRIGMVQTMDQYFFCYNAIVDEL 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		fn3	249..331	CDD:278470
		FN3	342..437	CDD:238020
		FN3	442..520	CDD:238020
		PTPc	646..911	CDD:214550	83/243 (34%)
		PTPc	676..911	CDD:238006	82/240 (34%)
		PTPc	935..1186	CDD:214550
		PTPc	963..1169	CDD:238006
PTP1	NP_001031266.1	PTPc_plant_PTP1	117..321	CDD:350496	73/208 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	163	1.000	Domainoid score	I1235
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40242
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19134
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910