Protein Alignment Ptp99A and PTPRN2

DIOPT Version :10

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001295197.1
• Gene: PTPRN2 / 5799
• HGNCID: 9677
• Length: 1038
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 67/292 - (22%)
• Similarity: 101/292 - (34%)
• Gaps: 62/292 - (21%)

  Fly   220 GQSSVPEYNV---DDVLRSGELLKIRGFWSESRSGGQQQGSGLAGNKRRMPGA-----------E 270
            |||:.|..|:   :|.:.:..:.:.|.....||...|..|...|......|.|           |
Human    57 GQSTSPPCNLIDNEDSIVAKYINRFRQAQPTSREDRQPAGPTSADFWWLQPTADSSGHLAAGAGE 121

  Fly   271 PPRKMHYRQPGTSSQDSNDQGRAPVLPGRSSLKSVDQQSEVASDSGTSAMDSLDEQKRLAIAAIQ 335
            |..:.....|..:...|.....||:...:.||.|        .:|....:::|..|.| |...::
Human   122 PTGRSAVTGPSPTGVSSTSLASAPLQKVKQSLNS--------WNSSLLDLETLSLQSR-AARLLK 177

  Fly   336 RDLHASSMRAMAHGAAALFSSG-SLSDVKQEPTEWDDLDDDNDSDEDVMILPEEVVKSKPA-ADG 398
            |.  .:|:...:..:..:.|.| |.|.|...|       |.|.|..     |:|.|...|. :..
Human   178 RS--KASLNDASSSSFPISSDGLSPSSVTFNP-------DSNKSSN-----PKEPVLGAPGPSQA 228

  Fly   399 KPKQSPQTSQAV--PDHYSLQQQQQQQSLPQPQPQQ------LP--PQLLAGQVPIDNDLQQQQV 453
            .|...|.:|||.  |:...|.|.:|::.|.|.....      ||  |.|.....|:      ..|
Human   229 IPAPRPASSQATLKPEDDILYQWRQRRKLEQSLQGAGDGTWVLPRMPALTTQTPPV------SAV 287

  Fly   454 QQVQQQQQP-------QQHLPEPSHSAHQQQP 478
            ....|..||       ....|.||.:.:.::|
Human   288 NLGSQDTQPNCTAPCGSVAQPPPSQAFYMERP 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020	6/18 (33%)
		FN3	243..337	CDD:238020	21/104 (20%)
		fn3	343..430	CDD:394996	24/90 (27%)
		FN3	442..520	CDD:238020	9/44 (20%)
		R5-PTPc-1	704..907	CDD:350397
		R5-PTP-2	989..1182	CDD:350398
PTPRN2	NP_001295197.1	RESP18	98..>152	CDD:464394	9/53 (17%)
		Receptor_IA-2	532..620	CDD:463293
		R-PTP-N2	750..1032	CDD:350458