DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ptp99A and PTPRE

DIOPT Version :10

Sequence 1:NP_651691.4 Gene:Ptp99A / 43469 FlyBaseID:FBgn0004369 Length:1397 Species:Drosophila melanogaster
Sequence 2:XP_047281532.1 Gene:PTPRE / 5791 HGNCID:9669 Length:733 Species:Homo sapiens


Alignment Length:141 Identity:23/141 - (16%)
Similarity:54/141 - (38%) Gaps:51/141 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   419 QQQQQSLPQPQPQQLPPQLLAGQVPIDNDLQQQQVQQVQ-------QQQQPQQHLPE-----PSH 471
            ::.::||.:.|..|     .|...|....::::::::::       :.|:.:..|..     |..
Human    41 RRMERSLRRSQSDQ-----KASSQPSTTPVEEERMKRLENLKIALHKMQKERDELRRILADYPGK 100

  Fly   472 SAHQQQPTESSMNCDLCSACFTNTDDLLQHIISFHGDAAEVLRKRSRMAEEETPINN--MRCE-- 532
            :.:.:...||.|.             ::||        .||:....:|:|:   ||.  ::|:  
Human   101 NLNDRNKFESEML-------------MMQH--------EEVMTDMKKMSEQ---INTALVKCKNL 141

  Fly   533 ------FCGKF 537
                  :|..|
Human   142 TLENDWYCRSF 152

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ptp99ANP_651691.4 FN3 140..236 CDD:238020
FN3 243..337 CDD:238020
fn3 343..430 CDD:394996 2/10 (20%)
FN3 442..520 CDD:238020 11/89 (12%)
R5-PTPc-1 704..907 CDD:350397
R5-PTP-2 989..1182 CDD:350398
PTPREXP_047281532.1 R-PTPc-E-1 198..426 CDD:350468
R-PTPc-E-2 513..722 CDD:350470
Blue background indicates that the domain is not in the aligned region.

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