Protein Alignment Ptp99A and Ptpn9

DIOPT Version :10

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_062625.2
• Gene: Ptpn9 / 56294
• MGIID: 1928376
• Length: 593
• Species: Mus musculus
• Alignment Length: 566
• Identity: 165/566 - (29%)
• Similarity: 258/566 - (45%)
• Gaps: 115/566 - (20%)

  Fly   422 TTKNEG----EPSDQIAQRTDVGGPSAPAIVNLTCHSQESI---TIRWRRPYEFYNTID----FY 475
            |.:.||    :|.::..:...:.|..  .|:|:...:..||   |.|...|::....:.    ||
Mouse    71 TRRKEGIVKLKPHEEPLRSEILSGKF--TILNVRDPTGASIALFTARLHHPHKSAQHVVLQALFY 133

  Fly   476 IIKTRLAGQDTHRDIRI--------NASAKELETAMILQNLTTNSY----YEVKVAAA------T 522
            ::...:...:|.|:..:        |.:..||:....:.||...::    .:|.:..|      .
Mouse   134 LLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVP 198

  Fly   523 FSVINPKKIVLGKFSESRIIQLQPNCEKLQPLLRQSHNDYNLAVLVGIIFSCFGIILIIMAFFLW 587
            :|:|:    :|.|......||:....|..|.|.|:...: ||.          |.:.|.:|  .|
Mouse   199 YSIIS----LLLKDKVRERIQILKTSEVTQHLPRECLPE-NLG----------GYVKIDLA--TW 246

  Fly   588 SRKCFHAAYYYLDDPPHHPN----------APQVDWE---VPVKIGDEIRAAVPVNEFAKHVASL 639
            :       :.:|.....||:          .|.:||:   ||   |..   |:.:.|...:|.:.
Mouse   247 N-------FQFLPQVNGHPDPFDEIILSSLPPALDWDSVHVP---GPH---AMTIQELVDYVNTR 298

  Fly   640 HADGDIGFSREYEAIQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNLDY 704
            ...   |...|||.|:.|.......|  |..|.|..||||.::...|.:||.|....|..:. ||
Mouse   299 QKR---GIYEEYEDIRRENPVGTFHC--SMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQT-DY 357

  Fly   705 INANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWP--KDG 767
            |||:|:|||::.:|:|||||||.:|:..||.|:|||:|.:|||.|...|.|||||..|||  ||.
Mouse   358 INASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDS 422

  Fly   768 VETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVL 832
            ...:|.:.|..:..|.|:.|...||:|.:.:.::|:|      |..:.:.:|||:|.|.....::
Mouse   423 RIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQ------VTHFQFLSWPDYGVPSSAASLI 481

  Fly   833 NFVK-----------------KSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVN 880
            :|::                 |.....|    |||||||||:|||||:..||..|.|:::...:|
Mouse   482 DFLRVVRNQQSMAVGNLGARSKGQCPEP----PIVVHCSAGIGRTGTFCSLDICLAQLEELGTLN 542

  Fly   881 VFGFLRHIRAQRNFLVQTEEQYIFLHDALVE------AIASGETNL 920
            ||..:..:|.||.|.:||.|||.|.:.|::|      .:.||.:.|
Mouse   543 VFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPSGHSLL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		FN3	243..337	CDD:238020
		fn3	343..430	CDD:394996	3/11 (27%)
		FN3	442..520	CDD:238020	17/96 (18%)
		R5-PTPc-1	704..907	CDD:350397	89/221 (40%)
		R5-PTP-2	989..1182	CDD:350398
Ptpn9	NP_062625.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		CRAL_TRIO_N	20..66	CDD:215024
		SEC14	90..240	CDD:214706	32/166 (19%)
		PTPc-N9	299..569	CDD:350391	109/285 (38%)