Protein Alignment Ptp99A and ptpn13

DIOPT Version :10

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_068072003.1
• Gene: ptpn13 / 560883
• ZFINID: ZDB-GENE-070410-72
• Length: 2525
• Species: Danio rerio
• Alignment Length: 370
• Identity: 123/370 - (33%)
• Similarity: 185/370 - (50%)
• Gaps: 64/370 - (17%)

  Fly   601 DPPHHPNAPQ----------VDW---EVPVK------------IGDEIRAAVPVNEFAK--HVAS 638
            |.|.:.:|||          :.|   ::|::            :.:|...::|:.:...  |..|
Zfish  2176 DAPLNDSAPQSSSGPLDEDEITWGSDDLPIENINSKFTEDGPIVTEEELTSLPLVKVVPDGHYTS 2240

  Fly   639 LHADGDIGFSR----------EYEAIQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLH 693
            .:.:..:...|          |:|.:||....|:  |...|..|||:||||.||..:|.:||.|.
Zfish  2241 TNLNTIVRMMRGLIEQKVPLQEFENLQNLRPLDE--CLIGQTKENKKKNRYKNIVPFDTTRVLLG 2303

  Fly   694 PTPGQKKNLDYINANFIDGYQKGHAF--IGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGR 756
            ...|      |||||||....|..:|  |..|||||.|...||:|:|||:..:|.|:|..||.|:
Zfish  2304 NDGG------YINANFIKMAVKDESFMYIACQGPLPTTLGDFWQMVWEQKSNVIAMMTQEVEGGK 2362

  Fly   757 RKCDMYWPKDGVETYGV---IQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNTEKLVYQYHYTN 818
            .||..|||........|   :||.|::::.:..:.:|.:::|.:      |.|..:.|...:||.
Zfish  2363 VKCQRYWPDTPRSPQMVDDRLQVTLVKDQHLDNFVIRLIELKDV------QTNELQRVTHLNYTG 2421

  Fly   819 WPDHGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFG 883
            |||||||..|..:|.|:  |...:...:|||:.|||||:||:||.|.:|.:|..|.:....::..
Zfish  2422 WPDHGTPTQPEQLLTFI--SYMRHIHLSGPIITHCSAGIGRSGTLICIDVVLGLISKDADFDISD 2484

  Fly   884 FLRHIRAQRNFLVQTEEQYIFLHDALVEAIASGETNLMAEQVEEL 928
            .:|.:|.||..:|||||||||.:..::..:..    |.||  |||
Zfish  2485 IVRTMRLQRQGMVQTEEQYIFCYQVILYVLRC----LQAE--EEL 2523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		FN3	243..337	CDD:238020
		fn3	343..430	CDD:394996
		FN3	442..520	CDD:238020
		R5-PTPc-1	704..907	CDD:350397	84/207 (41%)
		R5-PTP-2	989..1182	CDD:350398
ptpn13	XP_068072003.1	Protein Kinases, catalytic domain	48..225	CDD:473864
		Ubl1_cv_Nsp3_N-like	600..694	CDD:475130
		B41	605..809	CDD:214604
		FERM_C_PTPH13	805..905	CDD:270008
		PDZ1_PTPN13-like	1102..1193	CDD:467285
		PTN13_u3	1189..1366	CDD:465189
		PDZ2-PTPN13_FRMPD2-like	1364..1455	CDD:467254
		PDZ3_PTPN13_FRMPD2-like	1498..1587	CDD:467181
		PDZ4_PTPN13-like	1762..1845	CDD:467182
		PDZ5_PTPN13-like	1856..1942	CDD:467183
		PDZ5_DrPTPN13-like	1995..2072	CDD:467273
		PTPc-N13	2281..2514	CDD:350445	98/246 (40%)