Protein Alignment Ptp99A and Ptpn3

DIOPT Version :10

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_006538160.1
• Gene: Ptpn3 / 545622
• MGIID: 105307
• Length: 935
• Species: Mus musculus
• Alignment Length: 251
• Identity: 86/251 - (34%)
• Similarity: 133/251 - (52%)
• Gaps: 18/251 - (7%)

  Fly   671 PENKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFIDGYQKG----HAFIGTQGPLPDTFD 731
            |:|..||||.::..||.:||.|      :.|.|||||::::.....    :.:|.||||||:|..
Mouse   690 PQNLDKNRYKDVLPYDTTRVLL------QGNEDYINASYVNMEMPAANLVNKYIATQGPLPNTCA 748

  Fly   732 CFWRMIWEQRVAIIVMITNLVERGRRKCDMYWP-KDGVETYGVIQVKLIEEEVMSTYTVRTLQIK 795
            .||:::|:|:::::||:|.|.||||.||..||| ...:..:|:..::...|:....|..|.:
Mouse   749 QFWQVVWDQKLSLVVMLTTLTERGRTKCHQYWPDPPDIMDHGIFHIQCQTEDCTIAYVSREM--- 810

  Fly   796 HLKLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRT 860
               |....:...|..|....|..|||||.||.....|.|||...:.. .:..|.:||||||:|||
Mouse   811 ---LVTNTETGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVKYVRSLR-VDGEPALVHCSAGIGRT 871

  Fly   861 GTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAIASG 916
            |..:.::..:..|::...|.....:|.:|.||..:|||..||.|:.:|::.....|
Mouse   872 GVLVTMETAMCLIERNLPVYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEG 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		FN3	243..337	CDD:238020
		fn3	343..430	CDD:394996
		FN3	442..520	CDD:238020
		R5-PTPc-1	704..907	CDD:350397	71/207 (34%)
		R5-PTP-2	989..1182	CDD:350398
Ptpn3	XP_006538160.1	B41	53..244	CDD:214604
		FERM_C_PTPN4_PTPN3_like	238..331	CDD:270010
		PDZ_PTPN3-4-like	528..617	CDD:467190
		PTPc-N3	653..926	CDD:350448	85/248 (34%)