DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ptp99A and Egflam

DIOPT Version :9

Sequence 1:NP_651691.4 Gene:Ptp99A / 43469 FlyBaseID:FBgn0004369 Length:1397 Species:Drosophila melanogaster
Sequence 2:XP_006232075.1 Gene:Egflam / 365691 RGDID:1306592 Length:1013 Species:Rattus norvegicus


Alignment Length:391 Identity:90/391 - (23%)
Similarity:142/391 - (36%) Gaps:88/391 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   214 FRLLAVNKLGISPPSKESYYIVTLREAPTGKPIPTTAHNTSSTSVYISWKAPPPDTILGEFLGYR 278
            |.|||.:    .||...|......:....|.|:.......:.|:..|.||.|....  ...:||.
  Rat    11 FLLLACS----LPPGAVSLRTALRKSGKVGPPLDIKLGALNCTAFSIQWKTPKRSG--SSIVGYT 69

  Fly   279 ITYRPRDRDPN---DTKEIYIRDNTVESHE-IQNLQTYTQYKVTVQVFNPEGLG----PETTILV 335
            :.|.....|.:   .:..:.:..:|:.:.| |.:|:..|:|:|::..::..|.|    |.....:
  Rat    70 VFYSELGSDKSLREQSHNVPVGQDTLITEEVIGDLKPGTEYRVSIAAYSQTGKGRLSFPRHVTTL 134

  Fly   336 MTDEGVPSK-PQNLTILDVSANSITMSWHPPKNQNGA-IAGYHVFHIHDNQTGVEIVKNSRNSVE 398
            ..|..:|.: |....:|.||.:.:.:||.|.:|:..| |..|          .||.::...:...
  Rat   135 SQDSCLPPEAPHQPHVLVVSDSEVALSWRPGENEGSAPIQSY----------SVEFIRPDFDKSW 189

  Fly   399 TLIHFELQ-------NLRPYTDYRVIVKAFTTKNEGEPSDQIAQRTDVGGPSAPAIVNLTCHSQE 456
            |:|...||       .|.|.|:|:..|:|...                        ...:..||.
  Rat   190 TIIQERLQMDSMVIKGLDPDTNYQFAVRAMNA------------------------YGFSLRSQP 230

  Fly   457 SITIRWRRPYEF----YNTIDFYIIKTRLAGQDTHRDIRINASAKELETAMILQNLTTNSYYEVK 517
            |.|||...|.|.    |.  ..||..|.::..|       :||..||:..:        |:.|||
  Rat   231 SNTIRTLGPGEAGSGRYG--PGYITDTGVSEDD-------DASEDELDLDV--------SFEEVK 278

  Fly   518 VAAATFSVINPKK---IVLGKFSESRIIQ-----LQPNCEKLQPLLRQSHNDYNLAVLVGII-FS 573
            ...|| .|.|.|.   .|.....:||:.|     |......:.|...|.....::||:..:. .|
  Rat   279 PLPAT-KVGNKKSKKTSVSNSEMDSRLAQPTSASLPETTVAVPPTPAQRKGKNSVAVMSRLFDMS 342

  Fly   574 C 574
            |
  Rat   343 C 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ptp99ANP_651691.4 FN3 140..236 CDD:238020 7/21 (33%)
fn3 249..331 CDD:278470 19/89 (21%)
FN3 342..437 CDD:238020 24/103 (23%)
FN3 442..520 CDD:238020 21/81 (26%)
PTPc 646..911 CDD:214550
PTPc 676..911 CDD:238006
PTPc 935..1186 CDD:214550
PTPc 963..1169 CDD:238006
EgflamXP_006232075.1 FN3 36..133 CDD:238020 21/98 (21%)
FN3 142..236 CDD:238020 28/127 (22%)
LamG 387..537 CDD:238058
EGF_CA 556..598 CDD:238011
Laminin_G_2 637..763 CDD:280389
EGF_CA 786..816 CDD:238011
Laminin_G_2 864..989 CDD:280389
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0613
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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