Protein Alignment Ptp99A and Ptpn20

DIOPT Version :10

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001073618.1
• Gene: Ptpn20 / 306281
• RGDID: 1309812
• Length: 421
• Species: Rattus norvegicus
• Alignment Length: 293
• Identity: 99/293 - (33%)
• Similarity: 153/293 - (52%)
• Gaps: 32/293 - (10%)

  Fly   638 SLHADGDIGFSREYEAIQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNL 702
            :|....::...||:..::.....||.  :.....:|:.||||.:|..||.:||.|      .||.
  Rat   151 ALQKKEELDIIREFLELEEMIPPDDF--KSGYELQNRDKNRYRDILPYDSTRVPL------GKNK 207

  Fly   703 DYINANFID--GYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWP- 764
            |||||::|.  .:::.:.:|.||||||||.:.||:|:.|....:|.|||..:|.|..||..|||
  Rat   208 DYINASYIRIVNHEEEYFYIATQGPLPDTIEDFWQMVLENNCNVIAMITREIEGGVIKCCSYWPV 272

  Fly   765 --KDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNTEKLVYQYHYTNWPDHGTP-- 825
              |:.:| :....|.|...::...:.:|..||      .||.......|....:..|||||||
  Rat   273 SLKEPLE-FKHFHVLLENFQITQYFVIRIFQI------VKKSTGKSHSVKHLQFIKWPDHGTPAS 330

  Fly   826 -DHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIR 889
             |..:..:.:|:||..     .||::|||||||||||.:|.:|.:...|::....|:...:..:|
  Rat   331 ADFFIKYVRYVRKSHI-----TGPLLVHCSAGVGRTGVFICVDVVFCTIEKNYSFNIMNIVTQMR 390

  Fly   890 AQRNFLVQTEEQYIFLHDALVEAIASGETNLMA 922
            .||..::||:|||.|.::.::|.:    .||:|
  Rat   391 KQRFGMIQTKEQYQFCYEIVLEVL----QNLLA 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		FN3	243..337	CDD:238020
		fn3	343..430	CDD:394996
		FN3	442..520	CDD:238020
		R5-PTPc-1	704..907	CDD:350397	76/210 (36%)
		R5-PTP-2	989..1182	CDD:350398
Ptpn20	NP_001073618.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..116
		PTP_DSP_cys	209..415	CDD:475123	77/221 (35%)