DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ptp99A and Mylk

DIOPT Version :9

Sequence 1:NP_651691.4 Gene:Ptp99A / 43469 FlyBaseID:FBgn0004369 Length:1397 Species:Drosophila melanogaster
Sequence 2:NP_001099344.2 Gene:Mylk / 288057 RGDID:1310915 Length:1961 Species:Rattus norvegicus


Alignment Length:332 Identity:73/332 - (21%)
Similarity:114/332 - (34%) Gaps:112/332 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 AEAGKNVTIPCPGVNEH-------------SLVDTLVWKTASTTIAQFANRIP--------LLHS 93
            ||....||:...|.:|:             ||...|..::.:|...:.|::.|        ::..
  Rat  1222 AECSCQVTVDDAGTSENTKAPEMKSRRPKSSLTPVLGTESDATVKKKPASKTPTKAAMPPQIIQF 1286

  Fly    94 PRIQLLS-----DNFG------------------LQFSPSLASDTSE-----------------Y 118
            |..|.:.     :.||                  :|.|.::..:.||                 |
  Rat  1287 PEDQKVRAGEPVELFGKVTGTQPITCTWMKFRKQIQESENIRVENSESGSKLTILAARQEHCGCY 1351

  Fly   119 ICLV-NDRHIPEAIVDLLVQDVPDPPE-RPLLISFTSRSVNLSWAHSQHPRNAPVTHFIIETREG 181
            ..:| |.....:|.|:|.|.|.||||. .|......|.|:.|||..|.:...:.|..:.:|..:.
  Rat  1352 TLVVENKLSSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDT 1416

  Fly   182 EDGIWEQLARIYTKTNATSYQVTGLTPFTVYSFRLLAVNKLGISPPSKESYYIVTLREAPTGKPI 246
            ||.:|.:||    ...:||:.|..|.|...|.||:.|||..|.|.||:||..             
  Rat  1417 EDKVWTELA----TCRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESEL------------- 1464

  Fly   247 PTTAHNTSSTSVYISWKAPPPDTILGEFLGYRITYRPRDRDPNDTKEIYIRDNTVESHEIQNLQT 311
                                  |.:||          :..:|.|..|:...|......:.:.:..
  Rat  1465 ----------------------TAVGE----------KPEEPKDEVEVSDDDEKEPEVDYRTVTV 1497

  Fly   312 YTQYKVT 318
            .|:.||:
  Rat  1498 NTEQKVS 1504

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ptp99ANP_651691.4 FN3 140..236 CDD:238020 35/96 (36%)
fn3 249..331 CDD:278470 10/70 (14%)
FN3 342..437 CDD:238020
FN3 442..520 CDD:238020
PTPc 646..911 CDD:214550
PTPc 676..911 CDD:238006
PTPc 935..1186 CDD:214550
PTPc 963..1169 CDD:238006
MylkNP_001099344.2 I-set 42..132 CDD:254352
Ig 64..129 CDD:143165
I-set 165..254 CDD:254352
Ig 183..251 CDD:143165
23ISL 255..408 CDD:293226
I-set 410..500 CDD:254352
Ig 427..497 CDD:143165
I-set 510..596 CDD:254352
IGc2 523..586 CDD:197706
I-set 619..708 CDD:254352
Ig 636..704 CDD:143165
I-set 717..805 CDD:254352
Ig 720..805 CDD:299845
I-set 1141..1230 CDD:254352 3/7 (43%)
IGc2 1154..1220 CDD:197706
Ig 1281..1378 CDD:299845 19/96 (20%)
I-set 1281..1370 CDD:254352 14/88 (16%)
FN3 1374..1465 CDD:238020 35/129 (27%)
STKc_MLCK1 1504..1762 CDD:271093 0/1 (0%)
Pkinase 1507..1762 CDD:278497
I-set 1852..1942 CDD:254352
IGc2 1865..1932 CDD:197706
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0613
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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