DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ptp99A and Ptpn5

DIOPT Version :9

Sequence 1:NP_651691.4 Gene:Ptp99A / 43469 FlyBaseID:FBgn0004369 Length:1397 Species:Drosophila melanogaster
Sequence 2:NP_001157037.1 Gene:Ptpn5 / 19259 MGIID:97807 Length:541 Species:Mus musculus


Alignment Length:239 Identity:91/239 - (38%)
Similarity:134/239 - (56%) Gaps:14/239 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   675 RKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFIDGYQ-KGHAFIGTQGPLPDTFDCFWRMIW 738
            |||||..|....||||.|.....:.....|||||:|.||. :...:|.||||:..|...||||:|
Mouse   300 RKNRYKTILPNPHSRVRLTSPDPEDPLSSYINANYIRGYSGEEKVYIATQGPIVSTVADFWRMVW 364

  Fly   739 EQRVAIIVMITNLVERGRRKCDMYWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKK 803
            ::|..||||||| :|....||..|||::.|...|   |::..::|:.|...|      |:|...:
Mouse   365 QERTPIIVMITN-IEEMNEKCTEYWPEEQVVHDG---VEITVQKVIHTEDYR------LRLISLR 419

  Fly   804 QCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAE---AGPIVVHCSAGVGRTGTYIV 865
            :...|:.:..|.:|:|||..|||...|:|:.|::...|...|   ..||:||||||:||||.:|.
Mouse   420 RGTEERSLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCSPIIVHCSAGIGRTGCFIA 484

  Fly   866 LDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDAL 909
            .....:|::::.:|::......:|..|..::||.|||.|:|.|:
Mouse   485 TSICCQQLRREGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHAM 528

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ptp99ANP_651691.4 FN3 140..236 CDD:238020
fn3 249..331 CDD:278470
FN3 342..437 CDD:238020
FN3 442..520 CDD:238020
PTPc 646..911 CDD:214550 91/239 (38%)
PTPc 676..911 CDD:238006 90/238 (38%)
PTPc 935..1186 CDD:214550
PTPc 963..1169 CDD:238006
Ptpn5NP_001157037.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..55
PTPc-N5 274..531 CDD:350461 91/239 (38%)
Substrate binding. /evidence=ECO:0000250 472..478 4/5 (80%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0789
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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