Protein Alignment Ptp99A and Ptpn20

DIOPT Version :10

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_006518791.1
• Gene: Ptpn20 / 19256
• MGIID: 1196295
• Length: 463
• Species: Mus musculus
• Alignment Length: 296
• Identity: 104/296 - (35%)
• Similarity: 160/296 - (54%)
• Gaps: 38/296 - (12%)

  Fly   638 SLHADGDIGFSREYEAIQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNL 702
            :|....::...||:..::...:.||....::.  :|:.||||.:|..||.:||.|      .||.
Mouse   193 TLQKKEELDIIREFLELEQMTLPDDFNSGNTL--QNRDKNRYRDILPYDSTRVPL------GKNK 249

  Fly   703 DYINANFID--GYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWP- 764
            |||||::|.  .:::.:.:|.||||||:|.:.||:|:.|....:|.|||..:|.|..||..|||
Mouse   250 DYINASYIRIVNHEEEYFYIATQGPLPETIEDFWQMVLENNCNVIAMITREIECGVIKCYSYWPI 314

  Fly   765 --KDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKK---KKQCNTEKLVYQYHYTNWPDHGT 824
              |:.:| :....|.|....|...:|||..||    :||   |.||     |....:|.||||||
Mouse   315 SLKEPLE-FEHFSVFLETFHVTQYFTVRVFQI----VKKSTGKSQC-----VKHLQFTKWPDHGT 369

  Fly   825 P---DHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLR 886
            |   |..:..:.:|:||..     .||::|||||||||||.:|.:|.:...|::....::...:.
Mouse   370 PASADFFIKYVRYVRKSHI-----TGPLLVHCSAGVGRTGVFICVDVVFSAIEKNYSFDIMNIVT 429

  Fly   887 HIRAQRNFLVQTEEQYIFLHDALVEAIASGETNLMA 922
            .:|.||..::||:|||.|.::.::|.:    .||:|
Mouse   430 QMRKQRCGMIQTKEQYQFCYEIVLEVL----QNLLA 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		FN3	243..337	CDD:238020
		fn3	343..430	CDD:394996
		FN3	442..520	CDD:238020
		R5-PTPc-1	704..907	CDD:350397	81/213 (38%)
		R5-PTP-2	989..1182	CDD:350398
Ptpn20	XP_006518791.1	PTP_DSP_cys	251..457	CDD:475123	82/224 (37%)