DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp99A and ZK809.1

DIOPT Version :9

Sequence 1:	NP_651691.4	Gene:	Ptp99A / 43469	FlyBaseID:	FBgn0004369	Length:	1397	Species:	Drosophila melanogaster
Sequence 2:	NP_502200.1	Gene:	ZK809.1 / 191427	WormBaseID:	WBGene00014085	Length:	428	Species:	Caenorhabditis elegans

Alignment Length:	310	Identity:	66/310 - (21%)
Similarity:	115/310 - (37%)	Gaps:	66/310 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   646 GFSREYEA-IQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANF 709
            |..|:.|| ..|.|         .....:..:||:.:...|||:|:.:     |....||||.:.
Worm   137 GVRRDTEASCPNRC---------KMWQSHSSRNRHTDYKCYDHNRIIV-----QMCKDDYINGSK 187

  Fly   710 IDGYQKGHAFIGTQGPLPDTFDC---FWRMIWEQRVAIIVMITNLVERGRRKCD-MYWPKDGVET 770
            |:......:....|.|..|:.|.   |||:::.::...:.:|....|......| ::..:.|...
Worm   188 INVPHFTPSIYLVQLPKMDSVDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAWL 252

  Fly   771 YGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNTEKLVYQ--------------YHYTNWPD 821
            |.            :.:.|.|     .|::||:....:..|.:              |.:|.|..
Worm   253 YA------------NGFFVNT-----RKVEKKENAKADMFVVELLPEGCSNAVMCSVYLHTYWKP 300

  Fly   822 HGTPDH---PLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFG 883
            ...||.   .:...:.:.|:...|    .|.|:....|.||....:.|..:..|:.:.....:..
Worm   301 LFGPDRFGAQIRAAHQIAKNENGN----SPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISE 361

  Fly   884 FLRHIRAQRNFLVQTEEQYIFLHDA---LVEA-IASGETNLMAEQVEELK 929
            .:|.||.||...|.:..||:.|:.|   |::. :.||.     |.|.::|
Worm   362 IVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKLPSGH-----EVVSKIK 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		fn3	249..331	CDD:278470
		FN3	342..437	CDD:238020
		FN3	442..520	CDD:238020
		PTPc	646..911	CDD:214550	61/289 (21%)
		PTPc	676..911	CDD:238006	55/258 (21%)
		PTPc	935..1186	CDD:214550
		PTPc	963..1169	CDD:238006
ZK809.1	NP_502200.1	PTPc	146..386	CDD:214550	55/274 (20%)
ZK809.1	NP_502200.1	PTPc	159..386	CDD:304379	53/252 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810