DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp99A and Y116A8C.37

DIOPT Version :9

Sequence 1:	NP_651691.4	Gene:	Ptp99A / 43469	FlyBaseID:	FBgn0004369	Length:	1397	Species:	Drosophila melanogaster
Sequence 2:	NP_503038.1	Gene:	Y116A8C.37 / 191006	WormBaseID:	WBGene00013810	Length:	298	Species:	Caenorhabditis elegans

Alignment Length:	316	Identity:	69/316 - (21%)
Similarity:	105/316 - (33%)	Gaps:	77/316 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   613 WEVPVKI---GDEIRAAVPVNEFAKHVASLHADGDIGFSREYEAIQNECIS-----DDLPCEHSQ 669
            :||.||:   ..:.|....|.|..|.|.....|..:|  |.||..:.|...     |..|....:
Worm     5 FEVNVKVNRRNRQARKVKKVEELGKVVDRKEMDSPLG--RLYEEKKEERKEEKKEVDKEPWSGEE 67

  Fly   670 HPENKRKNRYLNIT-------AYDHSRVHLHPTPGQKKNLDYINA-----------NFIDGYQK- 715
            ..:....|.:...|       ..|:.:..:...|..|.|:..|.|           ...:|.:.
Worm    68 PAKRMVANGFFTTTNVGGTFKQTDNFKTPMDSCPSFKNNMHKIRAPDCPIPEEKLVKLANGPESF 132

  Fly   716 -----------GHAFIGTQGP----LPDTFDCFWRMIWEQRVAIIVMITNLVERGRRK-----CD 760
                       ....|.||.|    .|||.| |||||.::.:..:|:....:|...::     ..
Worm   133 ICAAKITVPDFNRTMILTQVPDLSRSPDTAD-FWRMIHQESIVSVVIAVMPLEVTLQQILPLLSG 196

  Fly   761 MYWPKDGVETYGVIQV--KLIEEEV-MSTYTVRTLQIKHLKLKKKKQCNTEKLVYQYHYTNWPDH 822
            .|      .|||.:.|  |.:|..| |:.|.:..|         ...|:...|...||..||...
Worm   197 TY------STYGKMFVNNKKVESAVGMTEYCLEIL---------PDGCSNSLLTTVYHMHNWRQK 246

  Fly   823 GTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNI 878
            ...:....::..::|....|...    |:....|.||.|.:     ..|.|:.:||
Worm   247 RGLEVVTDLVTTMEKVMKVNENS----VLMSMNGTGRAGIF-----QEKPIEFRNI 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		fn3	249..331	CDD:278470
		FN3	342..437	CDD:238020
		FN3	442..520	CDD:238020
		PTPc	646..911	CDD:214550	59/280 (21%)
		PTPc	676..911	CDD:238006	52/245 (21%)
		PTPc	935..1186	CDD:214550
		PTPc	963..1169	CDD:238006
Y116A8C.37	NP_503038.1	PTPc	87..283	CDD:214550	46/215 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810