Protein Alignment Ptp99A and hpo-7

DIOPT Version :10

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_494193.1
• Gene: hpo-7 / 183354
• WormBaseID: WBGene00016548
• Length: 285
• Species: Caenorhabditis elegans
• Alignment Length: 325
• Identity: 74/325 - (22%)
• Similarity: 121/325 - (37%)
• Gaps: 103/325 - (31%)

  Fly   722 TQGP-----LP--------------------DTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDM 761
            ||||     ||                    .|.|.|.:||.:.:...:||:.          |.
 Worm     4 TQGPIHWKTLPKSVDDVDECAQGVEPSRPPYSTMDKFLQMIVQTKATDVVMLG----------DF 58

  Fly   762 YWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNTEKLVYQYHYTNWPDHGTPD 826
            |                 |.:|:    :||::|.....|.||:.:|   :..|.|..|.....|:
 Worm    59 Y-----------------ENDVV----LRTIEITSNFSKSKKETHT---IRHYFYKGWIAQNGPE 99

  Fly   827 HPLPVLNF---VKKSSAANPAEAGPIVVHCSAGVGRTG----TYIVLDAMLKQIQQKNIVNV--F 882
            ....:||.   |:||.:        :|||||.|:||..    |.:....|:..::|...|.:  .
 Worm   100 LSREILNVFKAVRKSKS--------VVVHCSTGIGRAAAFAFTELAYQTMMLNMRQTPTVGLDYV 156

  Fly   883 GFLRHIRAQRNFLVQTEEQYIF----LHDALVEAIASGETNLMAEQVEELKNCTPYLE---QQYK 940
            ..::.:|:.|...:.|..|..|    |.|.::|...|.|||:..:|:.     ..||:   ::|:
 Worm   157 KLIQDLRSMRAGAIYTPMQLAFSIIMLLDFVLENELSKETNIKYQQIR-----NSYLDLRKRKYR 216

  Fly   941 NIIQFQPKDIHIASAMKQVNSIKNRGAIFPIEGSRVHLTPKPGEDGSDYINASWLHGF-RRLRDF 1004
            ...::.|      ...|.|:...|.      ||::  ..|||.:......:.|.:... :.|.||
 Worm   217 TSEEYMP------DGGKTVDIDLNE------EGNK--RKPKPKQPKEKITHQSLMDKIVKMLEDF 267

  Fly  1005  1004
             Worm   268  267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		FN3	243..337	CDD:238020
		fn3	343..430	CDD:394996
		FN3	442..520	CDD:238020
		R5-PTPc-1	704..907	CDD:350397	51/222 (23%)
		R5-PTP-2	989..1182	CDD:350398	4/17 (24%)
hpo-7	NP_494193.1	PTPc	<1..185	CDD:214550	51/222 (23%)