Protein Alignment Ptp99A and Y54F10BM.3

DIOPT Version :9

• Sequence 1: NP_651691.4
• Gene: Ptp99A / 43469
• FlyBaseID: FBgn0004369
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001368044.1
• Gene: Y54F10BM.3 / 175350
• WormBaseID: WBGene00021858
• Length: 622
• Species: Caenorhabditis elegans
• Alignment Length: 722
• Identity: 142/722 - (19%)
• Similarity: 237/722 - (32%)
• Gaps: 244/722 - (33%)

  Fly   247 PTTAHNTSSTSVYISWKAPPPDTI--LGEFLGYRITYRPRDRDPNDTKEIYIRDNTVESHEIQNL 309
            ||.|..||:|....|.|.||.:..  |.:.|         |..|   .|:::....:||..:...
 Worm    30 PTPAPPTSTTPPVSSTKPPPAEQFNSLTDIL---------DLIP---IEVWLVVLFLESAFVGAF 82

  Fly   310 QTYTQYKVTVQVFNPEGLGPETTILVMTDEGVPSKPQNLTILDVSANSITMSWHPPKNQNGAIAG 374
            ..|..:|  ||.:..|.:..|..          .:.:...:.:|||:         ||:|   ||
 Worm    83 GAYCYWK--VQQWRDEKMAREKA----------WERRLARVSEVSAS---------KNRN---AG 123

  Fly   375 YHVFHIHDNQTGVEIVKNSRNSVETLIHFELQNLR-------PYTDYRVIVKAFTTKNEGEPSDQ 432
                       ||:..|..|.|.:.|.|.:...|:       |..|  ||||  ..:...:|.::
 Worm   124 -----------GVDPAKRPRESAKWLKHVKEVTLKRGGVELLPMED--VIVK--NKEKFKKPQNE 173

  Fly   433 IAQR---------TDVGGPSAPAIVNLTCHSQESITIRWRRPYEFYNTIDFYIIKTRLAGQDTHR 488
            :.:.         .|:...|.|...|........:...|                        |.
 Worm   174 LRENEVWVERQTGPDIDKDSDPKTENALDEQDYQLEDGW------------------------HG 214

  Fly   489 DIRINASAKELETAMILQNLTTNSYYEVKVAAATFSVINPKKIVLGKFSESRIIQLQPNCEKLQP 553
            ...:|.:.||      .:.|.|...|...:.:          |:.||
 Worm   215 KSALNITRKE------FKKLFTKMSYSPSMCS----------IIPGK------------------ 245

  Fly   554 LLRQSHNDYNLAVLVGIIFSCFGIILIIMAFFLWSRKCFHAAYYYLDDPPHHPNAPQVDWEVPVK 618
                 ..|.:..|:..                 |...|                  |.::|:|::
 Worm   246 -----ERDPSKTVIAN-----------------WFEWC------------------QPEFEIPIE 270

  Fly   619 IGDEIRAAVPVNEFAKHVASLHADGDIGF--SREYEAIQNECISDDLPCEHSQHPENKRKNRYLN 681
            : ..:.|..|         .|..|..:..  |..|       :.||....|:.           .
 Worm   271 L-TAMSAGNP---------KLCRDPKVQAWDSTSY-------LVDDTHFIHAS-----------T 307

  Fly   682 ITAYDHSRVHLHPTPGQKKNLDYINANFI-----DGYQKGHAFIGTQGPLPDTFDCFWRMIWEQR 741
            :||           ||:    :||....|     |..:|||         |||.:.||||:|:.|
 Worm   308 VTA-----------PGK----EYIGKAIICQAPFDDKEKGH---------PDTRESFWRMVWDTR 348

  Fly   742 VAIIVMITNLVERGRRKCDMYWPKD--GVETYGVIQVKLIEE-EVMSTYTV-RTLQIKHLKLKKK 802
            ...:||...::|.|.:||..|:|.:  ..|.||..:|:|:|: |:::.:.: |.:::.....|..
 Worm   349 ATYVVMCCQIMENGVQKCGRYFPDETGATENYGFAEVQLLEKHEMLNGHLLTRKIELTSGTWKHS 413

  Fly   803 KQCNTEKLVYQYHYTNWPD----HGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTY 863
            ......:.:..:.:..|.:    .|  :..:...|:|...:..|   ..||:||.|.|.||...:
 Worm   414 DDDPPIRTITHFQFLKWKEGEGLEG--EMSMDAFNYVNHRTRNN---LDPIIVHSSLGTGRACAF 473

  Fly   864 IVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLH----DALVEAIASGETNL-MAE 923
            :..:.|.:.|..|.......|....|.:|...:|..:|..::.    :.|::.:....... |.|
 Worm   474 VGAEYMFQMINTKKCGTARFFQVDFRTKRLGALQNGKQLFWVQNMAFELLIKKLKMHHLKFEMEE 538

  Fly   924 QVEELKN 930
            |...|||
 Worm   539 QWNFLKN 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp99A	NP_651691.4	FN3	140..236	CDD:238020
		fn3	249..331	CDD:278470	20/83 (24%)
		FN3	342..437	CDD:238020	23/110 (21%)
		FN3	442..520	CDD:238020	11/77 (14%)
		PTPc	646..911	CDD:214550	64/283 (23%)
		PTPc	676..911	CDD:238006	59/251 (24%)
		PTPc	935..1186	CDD:214550
		PTPc	963..1169	CDD:238006
Y54F10BM.3	NP_001368044.1	Y_phosphatase	278..515	CDD:395053	66/292 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900