Protein Alignment stg and cdc25

DIOPT Version :10

• Sequence 1: NP_524547.1
• Gene: stg / 43466
• FlyBaseID: FBgn0003525
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001342797.1
• Gene: cdc25 / 2542632
• PomBaseID: SPAC24H6.05
• Length: 596
• Species: Schizosaccharomyces pombe
• Alignment Length: 606
• Identity: 143/606 - (23%)
• Similarity: 225/606 - (37%)
• Gaps: 213/606 - (35%)

  Fly    23 SSSSSINKMSGSRR----ARRSLELMSMDQ---EELSFYDDDVVPQDQQRSASPELMGLLSPEGS 80
            ||.|..|.:||.|.    |.|.|:||| |:   :||.|:    .|:.:..:::     |:.|.|.
pombe     6 SSLSFTNTLSGKRNVLRPAARELKLMS-DRNANQELDFF----FPKSKHIAST-----LVDPFGK 60

  Fly    81 PQRFQIVRQPKILPAMGVSSD-----H--------TPARSFRIFNSLSSTCSMESSMDDEYMELF 132
                   ......||..:::|     |        ||.|:  :|.|||  |::|:.:.::.:...
pombe    61 -------TCSTASPASSLAADMSMNMHIDESPALPTPRRT--LFRSLS--CTVETPLANKTIVSP 114

  Fly   133 EMESQSQQTALGFPSGLNSLISGQIKEQPAAK------SP-------------AGLSMR------ 172
            ..||.|.          ::|.......|||:|      ||             |.:::.
pombe   115 LPESPSN----------DALTESYFFRQPASKYSITQDSPRVSSTIAYSFKPKASIALNTTKSEA 169

  Fly   173 --------------RPSVRR--------------------------------------CLSMTES 185
                          ||:|.|                                      .||.|.|
pombe   170 TRSSLSSSSFDSYLRPNVSRSRSSGNAPPFLRSRSSSSYSINKKKGTSGGQATRHLTYALSRTCS 234

  Fly   186 NTNSTTT------------------------------PPPKTPETARDC--FKRPEPPASA---- 214
            .:::||:                              .|..:.|...|.  .:||.....|
pombe   235 QSSNTTSLLESCLTDDTDDFELMSDHEDTFTMGKVADLPESSVELVEDAASIQRPNSDFGACNDN 299

  Fly   215 ------NCSPIQ-----SKRHRCAAVEKENCPAPSPL-------SQVTISHPPPLRKCMSL---- 257
                  ..|||:     .|.::..|.......:|||:       ::......|.||:..|:
pombe   300 SLDDLFQASPIKPIDMLPKINKDIAFPSLKVRSPSPMAFAMQEDAEYDEQDTPVLRRTQSMFLNS 364

  Fly   258 ------NDAEIMSALARSENRNEPELIGDFSKAYALPLMEGRHRDLKSISSETVARLLKGEFSDK 316
                  ...:::....:...:.....|....:..:||....:...||.|:.||:..||.|:|.|.
pombe   365 TRLGLFKSQDLVCVTPKQSTKESERFISSHVEDLSLPCFAVKEDSLKRITQETLLGLLDGKFKDI 429

  Fly   317 VASYRIIDCRYPYEFEGGHIEGAKNLYTTEQILDEFLTVQQTELQQQQNAESGHKRNIIIFHCEF 381
            .....|||||:.||:.||||..|.||.|.:.|:|.||:...|.            |..::||||.
pombe   430 FDKCIIIDCRFEYEYLGGHISTAVNLNTKQAIVDAFLSKPLTH------------RVALVFHCEH 482

  Fly   382 SSERGPKMSRFLRNLDRERNTNAYPALHYPEIYLLHNGYKEFFESHVELCEPHAYRTMLDPAY-- 444
            |:.|.|.::...||.||..|::.||.|:|||:|:||.|||.|:|:|...|:|..|..|.|.::
pombe   483 SAHRAPHLALHFRNTDRRMNSHRYPFLYYPEVYILHGGYKSFYENHKNRCDPINYVPMNDASHVM 547

  Fly   445 --NEAYRHFR-----AKSKSW 458
              .:|..:|:     .::||:
pombe   548 TCTKAMNNFKRNATFMRTKSY 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stg	NP_524547.1	Cdc25	297..425	CDD:238788	56/127 (44%)
cdc25	NP_001342797.1	MIH1	108..596	CDD:227436	109/483 (23%)