Protein Alignment stg and Cdc25a

DIOPT Version :10

• Sequence 1: NP_524547.1
• Gene: stg / 43466
• FlyBaseID: FBgn0003525
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001397314.1
• Gene: Cdc25a / 12530
• MGIID: 103198
• Length: 522
• Species: Mus musculus
• Alignment Length: 461
• Identity: 148/461 - (32%)
• Similarity: 225/461 - (48%)
• Gaps: 74/461 - (16%)

  Fly    22 TSSSSSINKMSGSRRARRSLELMSMDQEELSFYDDDVVPQDQQ-------RSASPELMGLLSPEG 79
            |..:|...|:.|...|.:.....|:|.:.....|.|...:::.       |.||..:.     |.
Mouse   102 TRINSLPQKLLGCSPALKRSHSDSLDHDTFHLIDQDENKENEAFEFKKPIRPASRHIY-----EE 161

  Fly    80 SPQRFQIVRQPKILPAMGVSSDHTPARSFR-IFNSLSSTCSMESSMDDEYMELFEMES--QSQQT 141
            |...|  ..:....||..:||:.:.:.:|. :|...|...:..|..||.:::|.:.|:  ..::|
Mouse   162 SKDPF--THRQNSAPARMLSSNESESGNFSPLFIPQSPVKATLSDEDDGFIDLLDGENMKNDEET 224

  Fly   142 ALGFPSGLNSLISGQIKEQPAAKSPAGL--SMRRPSVRRC-LSMTESNTNSTTTPPPKTPETARD 203
                ||.:.||.:..:    ..:.||.|  .:..|...|| |..:.|...|:|....|..:.:.:
Mouse   225 ----PSCMASLWTAPL----VMRRPANLVGPVSDPKADRCGLFDSPSPCGSSTRAVLKRADRSHE 281

  Fly   204 CFKRPEPPASAN-----CSPIQSKRHRCAAVEKENCPAPSPLSQVTISHPPPLRKCMSLNDAEIM 263
                 |||....     .||:::         |.:.|.|:.|...::|       .||.....|.
Mouse   282 -----EPPRGTKRRKSVPSPVKA---------KADVPEPAQLPSQSLS-------LMSSPKGTIE 325

  Fly   264 SALARSENRNEPELIGDFSKAYALPLMEGRHRDLKSISSETVARLLKGEFSDKVASYRIIDCRYP 328
            :.|    :.:..:|||||||.|....:.|:|:|||.||.|.:|.:|.|:|:..:..:.|||||||
Mouse   326 NIL----DSDPRDLIGDFSKGYLFNTVSGKHQDLKYISPEIMASVLNGKFAGLIKEFVIIDCRYP 386

  Fly   329 YEFEGGHIEGAKNLYTTEQILDEFLTVQQTELQQQQNAESGHKRNIIIFHCEFSSERGPKMSRFL 393
            ||:|||||:||.||:..|::.|..|        :.....:..||.|::|||||||||||:|.|::
Mouse   387 YEYEGGHIKGAVNLHMEEEVEDFLL--------KNPIVPTDGKRVIVVFHCEFSSERGPRMCRYV 443

  Fly   394 RNLDRERNTNAYPALHYPEIYLLHNGYKEFF---ESHVELCEPHAYRTMLDPAYNEAYRHFRAKS 455
            |  :|:|..|.||.|||||:|:|..||||||   :||   |||.:||.|....:.|..:.||.||
Mouse   444 R--ERDRLGNEYPKLHYPELYVLKGGYKEFFLKCQSH---CEPPSYRPMHHEDFKEDLKKFRTKS 503

  Fly   456 KSWNGD 461
            ::|.|:
Mouse   504 RTWAGE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stg	NP_524547.1	Cdc25	297..425	CDD:238788	65/130 (50%)
Cdc25a	NP_001397314.1	Phosphodegron	73..83
		M-inducer_phosp	85..326	CDD:461962	56/259 (22%)
		KEN box	140..142		0/1 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..316		13/72 (18%)
		Cdc25	355..472	CDD:238788	63/126 (50%)