Protein Alignment CG11951 and pepN

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_415452.1
• Gene: pepN / 947253
• ECOCYCID: EG10696
• Length: 870
• Species: Escherichia coli
• Alignment Length: 920
• Identity: 198/920 - (21%)
• Similarity: 338/920 - (36%)
• Gaps: 259/920 - (28%)

  Fly   127 SLP--FSAKLQDQ--------LAGYYRSSYVNTVANETRWISVTQFEPAAARLAFPCFDEPGYKA 181
            :||  |:.|:.::        |.|.|:|...          ..||.|....|......|.|...|
E. coli    85 NLPERFTLKIINEISPAANTALEGLYQSGDA----------LCTQCEAEGFRHITYYLDRPDVLA 139

  Fly   182 SFAITLGYHK-KYTG-LSNMPVNETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLP 244
            .|...:...| ||.. |||  .|.....|......|..:::..|...||.|....||.....|..
E. coli   140 RFTTKIIADKIKYPFLLSN--GNRVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFT 202

  Fly   245 NGT----LFRTWARPNAIDQCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWG 305
            ..:    ....:.....:|:..:|.......:|:.||.||:::.|.....:||..|:.|||||.|
E. coli   203 TRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKG 267

  Fly   306 LVTFAESTLLYSPEYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEG--------FAT 362
            |..|....:|...:.::.:...:...::.||..|.|.||.||.:.|..|.|.||        |::
E. coli   268 LNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSS 332

  Fly   363 YVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLESSHPISRPIEMTSQISESFDEISYQKGSSV 427
            .:.|..|..|:      .:.:|..|.  |.:|:...:||| || :|..:::..:....|:||:.|
E. coli   333 DLGSRAVNRIN------NVRTMRGLQ--FAEDASPMAHPI-RP-DMVIEMNNFYTLTVYEKGAEV 387

  Fly   428 IRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLTQAAHKTGSLPKDYNIK-TIMDSWTLQ 491
            |||:|..||||.|:.|::.|.|::....|..|:..:::..|:          |:. :....|..|
E. coli   388 IRMIHTLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDAS----------NVDLSHFRRWYSQ 442

  Fly   492 TGYPVINVTRDYTSRTAKLSQERYLLN------TDVSRAHKGCWWVPLS---YTNQEEKDFNNTA 547
            :|.|::.|..||...|     |:|.|.      ....:|.|....:|.:   |.|:
E. coli   443 SGTPIVTVKDDYNPET-----EQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNE--------- 493

  Fly   548 PKEWMECTETGESVP--------KTIHDLPGPDQWVIFNN-----------QLSAPYKVNY---- 589
                      |:.:|        .::.::...:|..:|:|           :.|||.|:.|
E. coli   494 ----------GKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSD 548

  Fly   590 ------------DAQNW---KLLIET---LNSEDYHS-------IHVVN--RAQLIDDVLYFAWT 627
                        |...|   :.|:.|   ||...:..       :||.:  ||.|:|:.:
E. coli   549 QQLTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKI----- 608

  Fly   628 GEQDYEIALQVISYLERERELLPWKSAFDNLQFVSGILRQTPNFRFFKNFTRRLITPIYEHLNGI 692
               |..:|.:::: |....|:.......|.:....  :|:.        .||.|.|.:.:.|..|
E. coli   609 ---DPALAAEILT-LPSVNEMAELFDIIDPIAIAE--VREA--------LTRTLATELADELLAI 659

  Fly   693 -NDTVASE---EQQDKTILKAIVADWACSF------EVSDCVTQALSFYRSWRSEAN--PDEVNP 745
             |....||   |.:|  |.|..:.:....|      .::| |..:..|:     |||  .|.:..
E. coli   660 YNANYQSEYRVEHED--IAKRTLRNACLRFLAFGETHLAD-VLVSKQFH-----EANNMTDALAA 716

  Fly   746 VPLGIRGVVYC-TAIKHGCDEDWDFLWTRYQKANVATEKQIILDSLGCSQEVW-VLQRYLERNFD 808
            :...:...:.| .|:....|:.|.             :..:::|.       | :||
E. coli   717 LSAAVAAQLPCRDALMQEYDDKWH-------------QNGLVMDK-------WFILQ-------- 753

  Fly   809 GMGDIRKQDSTSVFQAIADSEVGFLLAKKYLMDNVDSISKF-----------YHPQSES----MS 858
                     :||....:.::..|.|..:.:.|.|.:.|...           :|.:..|    :.
E. coli   754 ---------ATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSGYLFLV 809

  Fly   859 ELLPPLS-----------EQIFTQRDYD-EFMNFMASSKDQLKDIEQTISQSLETMLINVQWKER 911
            |:|..|:           |.:...:.|| :....|.::.:|||.:| .:|..|
E. coli   810 EMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLE-NLSGDL------------ 861

  Fly   912 NYERFTRAIS 921
             ||:.|:|::
E. coli   862 -YEKITKALA 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	100/387 (26%)
		ERAP1_C	574..902	CDD:463368	76/410 (19%)
pepN	NP_415452.1	pepN	1..870	CDD:237585	198/918 (22%)