Protein Alignment CG11951 and LAP2

DIOPT Version :9

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_014353.1
• Gene: LAP2 / 855682
• SGDID: S000004990
• Length: 671
• Species: Saccharomyces cerevisiae
• Alignment Length: 768
• Identity: 166/768 - (21%)
• Similarity: 281/768 - (36%)
• Gaps: 220/768 - (28%)

  Fly    24 HFRLPTAL------RPQSYDVRILTQLENPDDF---H-------------FNGTVKIQIEVLQNT 66
            |..||.::      |...||   .:.|.|..||   |             .:|:|..|::.|...
Yeast    38 HKMLPLSIEQRRPSRSPEYD---QSTLSNYKDFAVLHTDLNLSVSFEKSAISGSVTFQLKKLHEG 99

  Fly    67 HNITLHSKDLTIDDTEITLSQIGGEETTENCITSTAVNPTHDFYILN--TCKELLAGQFYELSLP 129
            .|   .|.:|.:|.:.:.:.::..:.:..:........|.....::|  :|.:           .
Yeast   100 KN---KSDELHLDTSYLDVQEVHIDGSKADFQIEQRKEPLGSRLVINNASCND-----------N 150

  Fly   130 FSAKLQDQLAGYYRSSYVNTVANETRWIS-----------VTQFEPAAARLAFPCFDEPGYKASF 183
            |:..:|      :|::...|.   .:|::           .:|.|...||..|||||.|..|::|
Yeast   151 FTLNIQ------FRTTDKCTA---LQWLNSKQTKGGKPYVFSQLEAIHARSLFPCFDTPSVKSTF 206

  Fly   184 AITLGYHKKYTGLSNMPV--NETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNG 246
            ..::.        |.:||  :..|..::..|.....||:.:|:..||:..:..|.|..|.. |..
Yeast   207 TASIE--------SPLPVVFSGIRIEDTSKDTNIYRFEQKVPIPAYLIGIASGDLSSAPIG-PRS 262

  Fly   247 TLFR--------TWARPNAIDQCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMEN 303
            |::.        .|...|.:::....||   |::..||  :|....|..||     .:..|.||:
Yeast   263 TVYTEPFRLKDCQWEFENDVEKFIQTAE---KIIFEYE--WGTYDILVNVD-----SYPYGGMES 317

  Fly   304 WGLVTFAESTLLYSPEYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLC 368
            ..: |||..||:        ...:...:::||||||.|.|||||...|...|||||:..|:....
Yeast   318 PNM-TFATPTLI--------AHDRSNIDVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRI 373

  Fly   369 VEDIHPQ----------WRTLQ--LESMSNLLTIFRKDSLESSHPISRPIEMTSQISESFDEISY 421
            :..||.:          |..||  ::||        ||. |....:.:.:...:...::|..:.|
Yeast   374 IGAIHGEPTRHFSALIGWSDLQNSIDSM--------KDP-ERFSTLVQNLNDNTDPDDAFSTVPY 429

  Fly   422 QKGSSVIRMMHLFLGEEA-FRTGLKSYLEKYTYKNAEQ----DNLWESLTQAAHKTGSLPKDYNI 481
            :||.:::..:...||.:| |...::.|.:|:..|:.:.    |.|:|...:.
Yeast   430 EKGFNLLFHLETILGGKAEFDPFIRHYFKKFAKKSLDTFQFLDTLYEFYPEK------------- 481

  Fly   482 KTIMDS-----WTLQTGYP----VINVTRDYTSRTAK--LSQERYLLNTDVSRAHKGCWWVPLSY 535
            |.|:||     |..:.|.|    .|....|...:.|.  :...::|..|:..|:         .:
Yeast   482 KEILDSVDWETWLYKPGMPPRPHFITALADNVYQLADKWVEMAQHLKTTEDFRS---------EF 537

  Fly   536 TNQEEKDFNNTAPKEWME-CTETGESVPKTIHDLPGPDQWVIFNNQLSAPYKVNYDAQNWKLLIE 599
            ...:.||||:.....::| .|:.|.|..|     |....|..|
Yeast   538 NAIDIKDFNSNQLVLFLETLTQNGHSNKK-----PKDFDWAKF---------------------- 575

  Fly   600 TLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIA-----LQVISYLERE-RELLPWKSAFDNL 658
                      .|.:||.|  |:........|:.|:.     .|:.:.|:.| :.|..|......:
Yeast   576 ----------PVASRALL--DIYQDNIVKSQNAEVVFKMFKFQIFAKLQEEYKHLADWLGTVGRM 628

  Fly   659 QFVSGILRQTPNFRFFKNFTRRLITPIYEHLNGINDTVASEEQQDKTILKAIV 711
            :||      .|.:|...:..|||....::.   ..||.       ..|.||:|
Yeast   629 KFV------RPGYRLLNSVDRRLALATFDK---FKDTY-------HPICKALV 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	117/515 (23%)
		ERAP1_C	574..902	CDD:338125	27/144 (19%)
LAP2	NP_014353.1	leuko_A4_hydro	57..669	CDD:274120	161/749 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910