Protein Alignment CG11951 and TMA108

DIOPT Version :9

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_012129.1
• Gene: TMA108 / 854669
• SGDID: S000001399
• Length: 946
• Species: Saccharomyces cerevisiae
• Alignment Length: 1040
• Identity: 219/1040 - (21%)
• Similarity: 393/1040 - (37%)
• Gaps: 276/1040 - (26%)

  Fly    33 PQSYDVR--ILTQLENPDDFHFNGTVKIQIEVLQNTHNIT----------LHSKDL-------TI 78
            |..|::|  |..:..:|   :|.|:..|.::...|:..:.          ||||||       ||
Yeast    14 PSHYELRLEIDPKQSSP---NFKGSAIIHLKFNPNSTTLASIEDSFTQFKLHSKDLIVLSAHATI 75

  Fly    79 DDT--EITLSQIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQ------ 135
            ..|  ::.:||..|:..       :..|......:.|.|..:       ||:.:..|::
Yeast    76 GSTKFDLKISQDTGKHL-------SIFNSESPIQLSNDCPLI-------LSVQYVGKIRDIKTHH 126

  Fly   136 DQLAGYYRSSYVN----TVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGL 196
            |:..|.:::::::    |..|.   :..|..:|.:|...|||.|||..|::|.:.:....:|..:
Yeast   127 DKTFGIFKTNFMDRKTGTANNH---VVATHCQPFSASNIFPCIDEPSNKSTFQLNIATDAQYKAV 188

  Fly   197 SNMPVNETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSHKPS--------TLPNGTLFRTWA 253
            ||.||......:|...:: ..|.::..|:|.:..:|:.|.....:        |:| .:::..|.
Yeast   189 SNTPVEMVEALDSSQKHL-VKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEGDRTIP-VSIYAPWD 251

  Fly   254 RPNAIDQCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSP 318
            ..||.    :..:...|.|...|..|...:||||:|.:.:|..|..||||:|::|...:.||..|
Yeast   252 IANAA----FTLDTVQKYLPLLESYFKCPYPLPKLDFVLLPYLSDMAMENFGMITIQLNHLLIPP 312

  Fly   319 EYSSQEAKQETA-NIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVE---DIHPQWRT- 378
            ...:.|..:|.| .::.|||.|||.||.::...|..||.||.|||::|...:|   |:...|.:
Yeast   313 NALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHILEQNGDLSHYWTSE 377

  Fly   379 ----LQLESMSNLLTIFRKDSLESSHPI----SRPIEMTSQISESFDEISYQKGSSVIRMMHLFL 435
                .|:|.     |:.|..:..:...|    .|...:.||.|:.||..:|.||..::|.:.|..
Yeast   378 PYLLQQVEP-----TMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYTKGIIMLRSLQLAT 437

  Fly   436 GEEAFRTGLKSYLE---KYTYKNAEQDNLWESLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYPVI 497
            ||...:.||:|..|   .:..::.:..::|..:       |...|..||...:.|||...|.||:
Yeast   438 GESHLQKGLESVFEDTKTFHARSVKPMDIWNHI-------GKFLKSQNITNFVSSWTRTPGLPVV 495

  Fly   498 NV---TRDYTSRTAKLSQERYLLNTDVSRAHKGCWWVPLSYTNQEEKDFNNTAPKE--WMECTET 557
            .|   .:|..::| ||:|.|:                 ::..:.||||.....|.:  .......
Yeast   496 KVEVEEKDGKTQT-KLTQHRF-----------------INQLSTEEKDQLEDVPYQVPLFGVLPD 542

  Fly   558 GESVPKTI--------HDLPGPDQWVIFNNQLSAPYKVNYDAQ------NWKLLIETLNSED--- 605
            |:...|.:        .|.|    .::.|:.....|:|:|:::      |.|:..|||:..|
Yeast   543 GKMDTKNVLLTDRTLKFDYP----ILVINHLAQGYYRVSYESEECYALINDKITEETLSEIDLRK 603

  Fly   606 --------------YHSIHV----------------------------------VNRAQLIDDVL 622
                          .:|||:                                  ::||.|....|
Yeast   604 IFLDLSQFIGDEGFQNSIHLHGLFKILNHIASPSTKIASKYWDPLSKGLEVLQTIDRASLTSSKL 668

  Fly   623 Y--------------FAW--------TGEQDYEIALQVISYLERE------------RELLPWKS 653
            .              ..|        |...:.::..||: :|.:.            :.||....
Yeast   669 QSFLKKKIVIPLFNKIDWPHGEFDKSTNPHELKVMSQVL-FLNKNSAKCAELCQIYFKHLLQGPR 732

  Fly   654 AFDNLQFVSGIL----RQTPNFRFFKNF----TRRLITPIYEHLNGINDTVASEEQQDKTILKAI 710
            :...|:.|:.||    :...|.:.:|..    .|...|.|..|:..:.|..:||...  .|....
Yeast   733 SSVPLELVNSILVVVSQHCANIKQWKKIFDLVKRSSCTGITNHVINMYDQNSSETAM--LIQNGA 795

  Fly   711 VADWACSFEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHGCDEDWDFLWTRYQ 775
            :.......: ||.|.:.|:|..|      ..|...:.|.:.|              :::.:.:..
Yeast   796 IESLGFCLD-SDIVKKTLNFITS------NIESEGMELALFG--------------FNYNFKKRL 839

  Fly   776 KANVATEKQIILDSLGCSQEVWVLQRYLERNFD--GMGDIRKQDSTSVFQAIADSEVGFLLAKKY 838
            ..|...:.|::.::      :|   .:...|||  .....||..:|......|...:..::.:.:
Yeast   840 NKNEKPQDQVVRET------IW---EWYMGNFDQWARKATRKGTTTGDHLHKALRSISLIIFQMF 895

  Fly   839 LMDNVDSISKFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMASSKDQLKDIEQTISQSLETML 903
            :.|....|.||.:.:.|.:.:.|..|.:              :.:|..|.::..:||.:.|.:::
Yeast   896 VADEPQKIEKFINLEKEKLGQSLLSLDD--------------IWASVQQDEESRKTIRRDLASLV 946

  Fly   904  903
            Yeast   947  946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	129/509 (25%)
		ERAP1_C	574..902	CDD:338125	69/428 (16%)
TMA108	NP_012129.1	PepN	7..941	CDD:223385	218/1033 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010