Protein Alignment CG11951 and AOPEP

DIOPT Version :9

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001372995.1
• Gene: AOPEP / 84909
• HGNCID: 1361
• Length: 859
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 106/540 - (19%)
• Similarity: 190/540 - (35%)
• Gaps: 168/540 - (31%)

  Fly   164 PAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRPHESIPDYVWTSFEE-------- 220
            |...|..|||.:.|...:::..|:      ...::..|..:..:.:.|..:|   ||
Human   275 PINNRALFPCQEPPVAMSTWQATV------RAAASFVVLMSGENSAKPTQLW---EECSSWYYYV 330

  Fly   221 --SLPMSTYLVA-----------YSLNDFSHKPSTLPNGTLFR------------TWARPNAIDQ 260
              .:|.||:.:|           :|.||.:.:....|:...||            .:...:|..|
Human   331 TMPMPASTFTIAVGCWTEMKMETWSSNDLATERPFSPSEANFRHVGVCSHMEYPCRFQNASATTQ 395

  Fly   261 ----------------C-DYAAELGPKVLKYYEELFGIKFPLPKVDQIAVP-DFSAGAMENWGLV 307
                            | :....|.|..|.....:.| ..|..::|.:.|| :|.:..|.:..::
Human   396 EIIPHRVFAPVCLTGACQETLLRLIPPCLSAAHSVLG-AHPFSRLDVLIVPANFPSLGMASPHIM 459

  Fly   308 TFAESTLLYSPEYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDI 372
            ..::|.|..........        :.||:||.|||..:..:.||:.||:|||||:     :||:
Human   460 FLSQSILTGGNHLCGTR--------LCHEIAHAWFGLAIGARDWTEEWLSEGFATH-----LEDV 511

  Fly   373 HPQWRTLQ------LESMSNLLTIFR----KDSLESS---HPISRPI-EMTSQISES-------- 415
            .  |.|.|      ......|....|    :|.::.|   ..:.||. :.|...|:|
Human   512 F--WATAQQLAPYEAREQQELRACLRWRRLQDEMQCSPEEMQVLRPSKDKTGHTSDSGASVIKHG 574

  Fly   416 ------FDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLTQAAHKTGS 474
                  |.::.|.||..::|.:...||:|.:    .|:|.|:.:....|..|.:...|...:  :
Human   575 LNPEKIFMQVHYLKGYFLLRFLAKRLGDETY----FSFLRKFVHTFHGQLILSQDFLQMLLE--N 633

  Fly   475 LPK----DYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTDVSRAHKGCW------ 529
            :|:    :.:::.|...|...:|.|            ..|.:||        ||...|.
Human   634 IPEEKRLELSVENIYQDWLESSGIP------------KPLQRER--------RAGAECGLARQVR 678

  Fly   530 -----WVPLS------YTNQEEKDFNNTAPKEWMECTE-----------TGESVPKTIH----DL 568
                 |:.::      ...::|:.|....|.:.:...|           |.:|:.:|.|    |.
Human   679 AEVTKWIGVNRRPRKRKRREKEEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQDQDA 743

  Fly   569 PGPDQW--VIFNNQLSAPYK 586
            ....:|  :|..::.:..||
Human   744 EVRHRWCELIVKHKFTKAYK 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	84/408 (21%)
		ERAP1_C	574..902	CDD:338125	4/15 (27%)
AOPEP	NP_001372995.1	GluZincin	<244..652	CDD:417498	83/407 (20%)
		Nucleolar localization signal. /evidence=ECO:0000250|UniProtKB:Q8BXQ6	689..699		0/9 (0%)
		Leuk-A4-hydro_C	721..>771	CDD:401171	9/43 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910