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Protein Alignment CG11951 and Enpep

DIOPT Version :9

Sequence 1:	NP_001350853.2	Gene:	CG11951 / 43463	FlyBaseID:	FBgn0039656	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_071587.2	Gene:	Enpep / 64017	RGDID:	621228	Length:	945	Species:	Rattus norvegicus

Alignment Length:	927	Identity:	289/927 - (31%)
Similarity:	484/927 - (52%)	Gaps:	81/927 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 EGSTYDHFRLPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTIDDTE 82
            |...:.:||||..::|..||:.:...:|   :..:.|.|.|.:.:.::|.::.||     |.:|.
  Rat    76 ESGEWKNFRLPDFIQPVHYDLEVKVLME---EDRYTGIVSISVNLSKDTRDLWLH-----IRETR 132

  Fly    83 IT----LSQIGGEET-TENCITSTAVNPTHDFYILNTCKELLA---GQFYELSLPFSAKLQDQLA 139
            ||    |.:..||:. ...|..    ....::.::...::|.|   ...|.|::.|...|...|.
  Rat   133 ITKLPELRRPSGEQVPIRRCFE----YKKQEYVVIQAEEDLAATSGDSVYRLTIEFEGWLNGSLV 193

  Fly   140 GYYRSSYVNTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNET 204
            |:||::|  |...:|:.|:.|..||..||.:|||||||..||::.|:|.:.|:|:.||||||.:
  Rat   194 GFYRTTY--TEDGQTKSIAATDHEPTDARKSFPCFDEPNKKATYNISLIHPKEYSALSNMPVEK- 255

  Fly   205 RPHESIPDYVW--TSFEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRTWARPNAIDQCDYAAEL 267
               |...|..|  |:|.:|:|||||||.::::.|:....|..:|.....:.:||.....:|||.:
  Rat   256 ---EETLDNDWKKTTFMKSVPMSTYLVCFAVHQFTSIQRTSRSGKPLTVYVQPNQKQTAEYAANI 317

  Fly   268 GPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANI 332
            ...|..::|:.|.:::.|||:|:||:|||..||||||||||:.|:.|||.|..|:...:|..|::
  Rat   318 TKAVFDFFEDYFAMEYSLPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDPLLSASSNQQRVASV 382

  Fly   333 VAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLE 397
            |||||.||||||:|||.||.|||||||||::...|.|......|:.|....:.::|.:...|||.
  Rat   383 VAHELVHQWFGNIVTMDWWDDLWLNEGFASFFEFLGVNHAEADWQMLSQVLLEDVLPVQEDDSLM 447

  Fly   398 SSHPISRPIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLW 462
            ||||:...:...::|:..||.|||.||:|::||:..::..|.|:.|.:.|||.:.:|||:..:.|
  Rat   448 SSHPVVVTVSTPAEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLENFKFKNAKTSDFW 512

  Fly   463 ESLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLN--TDVSRAH 525
            :||.:|:::.        :|.:||:||.|.||||:.|     |....::|:|:||:  .|.|:..
  Rat   513 DSLEKASNQP--------VKEVMDTWTSQMGYPVVTV-----SGKQNVTQKRFLLDYKADPSQPP 564

  Fly   526 KG---CWWVPLSYTNQEEKDFNNTAPKEWMECTETGESVPKTIHDLPGPDQWVIFNNQLSAPYKV 587
            ..   .|.:|:.:|  |..:.|.|.   :......|.::..   :|.| |.::..|......|:|
  Rat   565 SALGYTWNIPIKWT--ENGNSNITV---YYRSNREGITLNA---NLSG-DGFLKINPDHIGFYRV 620

  Fly   588 NYDAQNWKLLIETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERELLPWK 652
            ||:|:.|..:.|||:| ::.:....:|:..|||....|.....|||.||.:..||..|::.|||:
  Rat   621 NYEAETWDWIAETLSS-NHMNFSSADRSSFIDDAFALARAQLLDYEKALNLTRYLTSEKDFLPWE 684

  Fly   653 SAFDNLQFVSGILRQTPN-FRFFKNFTRRLITPIYEHLNGINDTVASEEQQDKTILKAIVADWAC 716
            .....:.::..:...... :...:.:.|..:.||.:.| |..||.:...:    :|:|.|..:||
  Rat   685 RVISAVSYIISMFEDDRELYPLIETYFRSQVKPIADSL-GWQDTGSHITK----LLRASVLGFAC 744

  Fly   717 SFEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKH-GCDEDWDFLWTRYQKANVA 780
            .....:.:..|...:.:| .:.|    ..:|:.:|.:||...::: |.:..|::...:|||.::|
  Rat   745 KMGAGEALGNASQLFEAW-LKGN----ESIPVNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLA 804

  Fly   781 TEKQIILDSLGCSQEVWVLQRYLERNFDGMGDIRKQDSTSVFQAIADSEVGFLLAKKYLMDNVDS 845
            .||:.:|..|...::|.:|.||||...| ...|:.||..:|.:.|:.:..|..:|..::..|.|.
  Rat   805 QEKEKLLYGLASVKDVTLLARYLEMLKD-PNIIKTQDVFTVIRYISYNSYGKSMAWNWIQLNWDY 868

  Fly   846 ISKFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMASSKDQ---LKDIEQTISQSLETMLINVQ 907
            :...:......:..:: .::|...|:....:..:|.|...:.   .|..||.    |||:..|::
  Rat   869 LVNRFTINDRYLGRIV-TIAEPFNTELQLWQMQSFFAKYPNAGAGAKPREQV----LETVKNNIE 928

  Fly   908 WKERNYERFTRAISKHF 924
            |.:.|    .::||:.|
  Rat   929 WLKLN----RKSISEWF 941

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.