Protein Alignment CG11951 and RNPEP

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_064601.3
• Gene: RNPEP / 6051
• HGNCID: 10078
• Length: 650
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 91/369 - (24%)
• Similarity: 147/369 - (39%)
• Gaps: 80/369 - (21%)

  Fly   160 TQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETR-PHESIPDYVWTSFEESLP 223
            ||.:....|..|||||.|..|..::..:.....:|.:.:....|.| |::..       |:...|
Human   168 TQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFF-------FQMCQP 225

  Fly   224 MSTYLVAYSLNDFSHKPSTLPNGTLFRTWARPNAIDQC---------DYAAE----LGPKVLKYY 275
            :.:||:|.::.|.    .:...|...|.||.|..||..         ::.|.    .||.|...|
Human   226 IPSYLIALAIGDL----VSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRY 286

  Fly   276 EELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANIVAHELAHQ 340
            :.||     :|       |.|..|.||| ..:||....||        ...:..|:::.||::|.
Human   287 DLLF-----MP-------PSFPFGGMEN-PCLTFVTPCLL--------AGDRSLADVIIHEISHS 330

  Fly   341 WFGNLVTMKWWTDLWLNEGFATY-----------VASLCVEDIHPQWRTLQLESMSNLLTIFRKD 394
            |||||||...|.:.||||||..|           .|..|:|  ....|.|..:.|         |
Human   331 WFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLE--AATGRALLRQHM---------D 384

  Fly   395 SLESSHPISR---PIEMTSQISESFDEISYQKGSSVIR-MMHLFLGEEAFRTGLKSYLEKYTYKN 455
            .....:|:::   .||......::::|..|:||...:. :.||...::.|.:.||:|:.::.:::
Human   385 ITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRS 449

  Fly   456 AEQDNL----WESLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYP 495
            ...|:.    .|...:...|...:...:.    .|.|....|:|
Human   450 ILADDFLDFYLEYFPELKKKRVDIIPGFE----FDRWLNTPGWP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	89/362 (25%)
		ERAP1_C	574..902	CDD:463368
RNPEP	NP_064601.3	M1_LTA4H	24..484	CDD:341062	89/362 (25%)
		Leuk-A4-hydro_C	530..644	CDD:462686