Protein Alignment CG11951 and trhde.2

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_690889.3
• Gene: trhde.2 / 562409
• ZFINID: ZDB-GENE-070705-89
• Length: 994
• Species: Danio rerio
• Alignment Length: 928
• Identity: 308/928 - (33%)
• Similarity: 493/928 - (53%)
• Gaps: 73/928 - (7%)

  Fly    24 HFRLPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTIDDTEI-TLSQ 87
            |.|||..|||:.||:|:...:||   |.|:|.|.|:.|.:.:|..|.|||..|.:|...: :.|:
Zfish   107 HLRLPATLRPRHYDLRLTVHMEN---FSFSGEVNIEFECVNSTKLIVLHSDRLELDKVLVFSDSK 168

  Fly    88 IGGEETTENCITSTAVNPTHDF-------YILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSS 145
            ..|           |:.....|       |::...:|:...:.|::::.|:|.::.:|.|::|||
Zfish   169 KAG-----------AMRIQRRFHYQPKQVYVIALHREMKPLRTYKINITFTAHIEHELLGFFRSS 222

  Fly   146 YVNTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRPHESI 210
            |:  :..|.|:::||||.|..||.||||||||.|||:|.::|.:...|..||||||..|...|.
Zfish   223 YM--LNGERRFLAVTQFSPTHARKAFPCFDEPIYKATFRVSLKHESLYQSLSNMPVEATTSDED- 284

  Fly   211 PDYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRTWARPNAID--QCDYAAELGPKVLK 273
             .:|...|..:..||||.:|:::.:|::|.:...||.|.|.:|||:||.  ..|||..:..::|:
Zfish   285 -GWVTNHFSMTPRMSTYYLAWAVCNFTYKEAVADNGVLIRLYARPDAIQSGSGDYALRITKRLLQ 348

  Fly   274 YYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANIVAHELA 338
            :|::.|.:|:.|||:|.:|||.....|||||||..|.|..:|..|:.||...:.|...:|.||:.
Zfish   349 FYQDYFKVKYSLPKLDLLAVPKHPYAAMENWGLSVFVEQKILLDPDVSSFSYQMELTMVVVHEIC 413

  Fly   339 HQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMSNLL-TIFRKDSLESSHPI 402
            |||||:|||..||.|:||.||||.|...:..:.:.|:|...:...::::| .:...|.|.|||||
Zfish   414 HQWFGDLVTPVWWEDVWLKEGFAHYFEYIGTDFLFPKWNMEKQRFLTDVLHEVMLLDGLASSHPI 478

  Fly   403 SRPIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLTQ 467
            |:.:...:.|...||.|:|:||:::|||:...:|:..|:..|..||..:.|.||.:|:||..|::
Zfish   479 SQQVFEATDIDRVFDWIAYKKGAALIRMLANVMGQTLFQRALNDYLMTHMYGNAARDDLWNKLSE 543

  Fly   468 AAHKTGSLPKDYNIKTIMDSWTLQTGYPVINVTR-DYTSRTAKLSQERYLLNTDVSRAHKGC--- 528
            |..:.|   ||.||..:||.||||.||||:.::: |....:..:|||.::.:||....:...
Zfish   544 AMQREG---KDINITQVMDRWTLQMGYPVVTISKNDSLDNSITISQEHFVYDTDAKIQNPELFNK 605

  Fly   529 ---WWVPLSYTNQEEKDFNNTAPKEWMECTETGESVPKTIHDLPGPDQWVIFNNQLSAPYKVNYD 590
               |.:||:......... :|....|:    |.:|....:..:.| :.|::.|...:..::||||
Zfish   606 SFQWQIPLTLAVGNASHI-STETIIWV----TNKSEAHRVGHVVG-ETWLLGNINQTGYFRVNYD 664

  Fly   591 AQNWKLLIETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERELLPWKSAF 655
            ..||||||:.| :.:...|.|.|||.|||||...|..|.....:.||:||||.:|.|.|||.:|.
Zfish   665 LHNWKLLIQQL-TRNPTIISVGNRAGLIDDVFNLARAGYLPQNVPLQMISYLSQETEFLPWHAAS 728

  Fly   656 DNLQFVSGILRQTPNFRFFKNFTRRLITPIYEHLNG---------INDTVASEEQQDKTILKAIV 711
            ..|..:..:|.:|.:...|.::..|.:.|.|..|..         ::....:||.|.:.|:
Zfish   729 RALYQLDKLLDRTLDHSLFSDYVLRQVEPKYHKLGWPATSPDGSLMHSAYQTEELQREVIM---- 789

  Fly   712 ADWACSFEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHGCDED-WDFLWTRYQ 775
              .||||....|..||:|....|.|    ...|.:|..:|.:||||.:.. .||| |:|:|.::.
Zfish   790 --LACSFGNKHCHRQAVSLISDWIS----SNKNRIPPNVRDIVYCTGVSL-MDEDVWEFIWMKFH 847

  Fly   776 KANVATEKQIILDSLGCSQEVWVLQRYLERNFDGMGD-IRKQDSTSVFQAIADSEVGFLLAKKYL 839
            .:...:||:::|::|.||..:::|.|.|  |.....| :..||...|...:|.:.:|..||.:|.
Zfish   848 SSTAVSEKKVLLEALTCSDNIFLLNRLL--NLSLTSDLVPDQDVIDVIIHVARNPLGRHLAWRYF 910

  Fly   840 MDNVDSISKFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMASSKDQLKDIEQTISQSLETMLI 904
            .:..|.::..|.......|:|:..::|.:.|:.:.:|...|:.:|..   :.....::::|.:..
Zfish   911 REKWDILNSRYGEALFMNSKLISGVTEFLNTEAELNELKEFILTSGG---ESAPAFARAVEIVQA 972

  Fly   905 NVQWKERNYERFTRAISK 922
            ||:|.....|:|.:.:.|
Zfish   973 NVKWHILFQEQFYQWLRK 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	173/465 (37%)
		ERAP1_C	574..902	CDD:463368	101/338 (30%)
trhde.2	XP_690889.3	None