Protein Alignment CG11951 and anpeplb

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_001038326.1
• Gene: anpeplb / 558452
• ZFINID: ZDB-GENE-030131-4781
• Length: 946
• Species: Danio rerio
• Alignment Length: 937
• Identity: 301/937 - (32%)
• Similarity: 478/937 - (51%)
• Gaps: 109/937 - (11%)

  Fly    23 DHFRLPTALRPQSYDVRI-------LTQLENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTIDD 80
            :..|||.:|.|:||:|.:       :|.......:.|.|...:::...:.:..:.||..::.:..
Zfish    60 ESLRLPDSLIPESYNVFLQPYLYAAITNNYTEQSYLFTGNSTVRVNCTKTSSRVFLHVHNINVTA 124

  Fly    81 TEITLS-----------QIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKL 134
            .|:..|           ||...||  |.:         |.::....||   ...|::...|..:|
Zfish   125 VEVRKSDTNEKLPLKGYQIFKNET--NFL---------DIHLEVAIKE---NGTYDIFTEFEGEL 175

  Fly   135 QDQLAGYYRSSYVNTVA---NETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGL 196
            .:.|.|:|.|.|.....   :|.|:::.:..:|..||..|||||||..||.|.||:.:..:....
Zfish   176 LEDLTGFYASRYTGKGTDDEDEERFLATSLLQPTDARTVFPCFDEPAMKAVFTITIIHRPEIRAR 240

  Fly   197 SN-------MPVNETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRT--- 251
            ||       :.:|.|       |::.|:|:.:..||:||:.:.:.| :|..|.:..||  ||
Zfish   241 SNEDGDPRTIQINGT-------DWIRTTFKPTKKMSSYLLGFIIYD-THTFSYVSKGT--RTKIH 295

  Fly   252 -WARPNAID--QCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAEST 313
             ..|..|||  ..|||.|....:|.:||.:||:::|:.|:||||:|||...||||||.:::.||.
Zfish   296 VHGRSEAIDAGHADYALETTETILSHYENIFGLRYPMSKIDQIALPDFGVRAMENWGFISYQESG 360

  Fly   314 LLYSPEYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRT 378
            |||..|.:|...:::...::|||||||||||||||.||.||||.||||||::...||.:  .|..
Zfish   361 LLYDKETASTFDEEQVTTLIAHELAHQWFGNLVTMSWWNDLWLKEGFATYMSYKGVEAV--GWDL 423

  Fly   379 LQLESMSNLLTIFRKDSLESSHPISR---PIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAF 440
            ..|..:..:.|.|:.|||.:|||:|.   .::.:|||||.||:|:|.||::|:||:...:||..|
Zfish   424 KDLIVLREIQTAFQMDSLNTSHPLSMNAYDVQTSSQISELFDDITYSKGAAVLRMLATRMGENEF 488

  Fly   441 RTGLKSYLEKYTYKNAEQDNLWESLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYPVINVTRDYTS 505
            ..|:|.||.|:.::|....:|||.|....|        ..:...|.:||.:.||||:.:..|
Zfish   489 MKGVKMYLSKFQFENTVPKDLWECLNMDTH--------IKVDEFMKTWTEEVGYPVLTIITD--- 542

  Fly   506 RTAKLSQERYLLNTDVSRAHKGCWWVPLSYTNQEE--KDFNNTAPKEWMECTETGESVPKTIHDL 568
             |...|||::||..:  ..|...|.:|:.|...:.  |:|.|.       .|:.|   |..|.|.
Zfish   543 -TGDTSQEQFLLKKE--GGHDSLWHIPIKYMTLKAGVKEFPNF-------FTDKG---PDPIPDF 594

  Fly   569 P-GPDQWVIFNNQLSAPYKVNYDAQNWKLLIETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDY 632
            . |.|.|::.|...:..|:||||.:||..|...| .:::..|.::||.|||||....|.....:.
Zfish   595 KIGKDNWLLANINCTGFYRVNYDEENWNRLTAQL-QKNHRIIPLINRGQLIDDAFNLARAHRLNV 658

  Fly   633 EIALQVISYLERERELLPWKSAFDNLQFVSGILRQTPNFRFFKNFTRRLITPIYEHLN--GINDT 695
            .|||.:..||..:.|.:||:||..||.|.:.:..::..:.....:.|.|:||:||...  .||.|
Zfish   659 TIALNLTKYLINDLEYIPWESALKNLDFFTLMFDRSEVYGPIMKYLRNLVTPLYEEYEEYTINGT 723

  Fly   696 VASEEQQDK-TILKAIVADWACSFEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAI 759
            :..|:..|: ..:.||..  |||..:.:|:|.|...:..:::.:||  ::|   .:|..|||:|:
Zfish   724 IPIEKYTDQCNQVNAITV--ACSNGLPECITMAKDLFSDYKNGSNP--IHP---NLRRAVYCSAV 781

  Fly   760 KHGCDEDWDFLWTRYQKANVATEKQIILDSLGCSQEVWVLQRYLERNFDGMGDIRKQDSTSVFQA 824
            ..|.::||:::|..||||.||.||..:..:|.|::|:|:|.|||:...: ...|||.|..|....
Zfish   782 ASGDEDDWEYVWEEYQKATVAAEKDKLRYALSCTKEIWLLNRYLQYTLE-PSKIRKMDMVSTISY 845

  Fly   825 IADSEVGFLLAKKYLMDNVDSISKFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMASSKDQLK 889
            ||.:..|..||..::..:...|::.|.....|:..||..::::..|:.:.:|....   .::|::
Zfish   846 IAQNVAGQPLAWDFIRGHWSYITQEYGAGIISLGSLLDVVTKRFSTEVELEELKQL---QREQIQ 907

  Fly   890 D----IEQTISQSLETMLINVQWKERN 912
            |    ..:.:.|.:|....|:.|.:.|
Zfish   908 DDKWIAARALEQVIERTAANIIWVKEN 934

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	166/491 (34%)
		ERAP1_C	574..902	CDD:463368	101/334 (30%)
anpeplb	NP_001038326.1	M1_APN-Q_like	71..530	CDD:341064	166/492 (34%)
		ERAP1_C	601..926	CDD:463368	101/336 (30%)