Protein Alignment CG11951 and anpepa

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: XP_682987.2
• Gene: anpepa / 555478
• ZFINID: ZDB-GENE-130530-595
• Length: 960
• Species: Danio rerio
• Alignment Length: 923
• Identity: 311/923 - (33%)
• Similarity: 481/923 - (52%)
• Gaps: 66/923 - (7%)

  Fly    22 YDHFRLPTALRPQSYDVRILTQL--ENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTI---DDT 81
            :|.:|||..|.||.|::.:..:|  :....:.|.|...:....::.|..|.:||..|.:   :..
Zfish    63 WDKYRLPDTLSPQYYNITLWPRLVMDANGMYIFTGISDVMFTCVKKTDLILIHSNKLNLTLFNGR 127

  Fly    82 EITLSQIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSSY 146
            ...|:.:.|  .|...|.||.:.....:.::....:|..|:.|.|...|:.:|.|.|.|:|||.|
Zfish   128 HAKLTGMSG--VTAPAIKSTWLQTQTQYLVIQLKGKLNPGKSYWLHTEFTGELADDLEGFYRSEY 190

  Fly   147 VNTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRPHESIP 211
            :..  .|.:.|::||.:...||.||||||||..||.|.|.|.:.:..|.|||.  .|.|..:.|.
Zfish   191 MED--GEKKIIAITQMQATYARKAFPCFDEPAMKAVFNIILIHDRGMTALSNS--QEIRTEDVII 251

  Fly   212 D---YVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRTWARPNAID--QCDYAAELGPKV 271
            |   ...|:||.:..|||||||:.::|||:..:....|.|.|.|||..|||  |.|||..:...:
Zfish   252 DEMPVTRTTFEPTARMSTYLVAFVVSDFSYINNEDKAGVLVRIWARKKAIDDGQGDYALSITQPI 316

  Fly   272 LKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPEYSSQEAKQETANIVAHE 336
            |:::|..:...:||.|.||:|:|||::||||||||||:.|:.|||.|:.|:...||..|.:|:||
Zfish   317 LEFFESYYNTSYPLSKSDQVALPDFNSGAMENWGLVTYRETALLYDPQTSANGNKQRIATVVSHE 381

  Fly   337 LAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLESSHP 401
            |||.|||||||:|||.|||||||||:||..|..:...|.|.......:.::...|..|||.||||
Zfish   382 LAHMWFGNLVTLKWWNDLWLNEGFASYVEYLGADHAEPTWNIKDQIILYDMQRAFAVDSLTSSHP 446

  Fly   402 ISR---PIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWE 463
            :||   .:...::|||.|..|||.||::|::|:..||.|..|..||.:||:::.:.::...:||:
Zfish   447 LSRKEEEVNTPAEISEMFSTISYSKGAAVLKMLSEFLTEPVFAKGLSNYLKQFAFGSSVHSDLWD 511

  Fly   464 SLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTD--VSRAHK 526
            .|.::..:...:....::..||..|.||.|:|||.:    .:||..:||:.:|:..|  |.|..:
Zfish   512 HLQKSLDQAPGMKLPRSVHEIMSRWILQMGFPVITI----DTRTGNVSQKHFLVEKDAVVERNSE 572

  Fly   527 GC--WWVPLSYTNQEEKDFNNTAPKEWMECTETGESV----PKTIHDLP---GPDQWVIFNNQLS 582
            ..  |:||:                :||:..:..:.:    ...||. |   ...:||:.|:.:|
Zfish   573 FNYEWFVPI----------------KWMKKGQVQDQMWLLQKSAIHK-PMKVSKGEWVLANHNVS 620

  Fly   583 APYKVNYDAQNWKLLIETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERE 647
            ..::||||..||:.|:..|.: ::.:|.||||||::||....|.....:..:||:...||.||||
Zfish   621 GYFRVNYDHGNWERLLSQLET-NHQTIPVVNRAQILDDAFNLARASIINITLALRTTKYLVRERE 684

  Fly   648 LLPWKSAFDNLQFVSGILRQTPNFRFFKNFTRRLITPIYEHLNGI--NDTVASEEQQDKTILKAI 710
            .:||::|..:|.:...:..:...:...:.:.::.:.|::||...|  |.|.......|: ..:.|
Zfish   685 YIPWEAALRSLNYFFQLFDRNEVYGALQAYLKKQVKPLFEHFGTISSNWTKVPNGHTDQ-FTQII 748

  Fly   711 VADWACSFEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHGCDEDWDFLWTRYQ 775
            ....||...|..|.....|:::.|..  || .|||:...:|..|||.||..|..::|:|.|..:|
Zfish   749 ALSLACGTGVEGCREITKSWFKKWMQ--NP-RVNPIHPNLRSTVYCNAIAAGGADEWNFGWQMFQ 810

  Fly   776 KANVATEKQIILDSLGCSQEVWVLQRYLERNFDGMGDIRKQDSTSVFQAIADSEVGFLLAKKYLM 840
            ||.||.|...:..:|.|::..|:|.||||.:.: ...|||||:||....||.:.:|..||..::.
Zfish   811 KATVAAEAVKLRAALACTKVPWLLNRYLEYSIN-PEKIRKQDATSTIGYIASNVIGQPLAWNFVR 874

  Fly   841 DNVDSISKFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMASSKDQLK----DIEQTISQSLET 901
            .|.|...|.|...|.:.|.|:..::.:..|..:..:...|   .||..:    ...|.:.|::|.
Zfish   875 ANWDYFFKVYGTGSFTFSRLISDITSKFCTPFELSQLKRF---QKDNAETGFGSGTQALQQAIER 936

  Fly   902 MLINVQWKERNYE 914
            ....::|...|.|
Zfish   937 TTAKIKWLAENKE 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	176/467 (38%)
		ERAP1_C	574..902	CDD:463368	103/333 (31%)
anpepa	XP_682987.2	None