Protein Alignment CG11951 and rnpep

DIOPT Version :10

• Sequence 1: NP_001350853.2
• Gene: CG11951 / 43463
• FlyBaseID: FBgn0039656
• Length: 842
• Species: Drosophila melanogaster
• Sequence 2: NP_001002741.2
• Gene: rnpep / 437014
• ZFINID: ZDB-GENE-040718-241
• Length: 624
• Species: Danio rerio
• Alignment Length: 728
• Identity: 161/728 - (22%)
• Similarity: 273/728 - (37%)
• Gaps: 209/728 - (28%)

  Fly    23 DHFRLPTALRPQSYDVRILTQLENPDDF---HFNGTVKIQIEVLQNTHN---ITLHSKDLTIDDT 81
            :||.|         |:::        ||   ..:||..|:::.:|::.:   :.:|.   ::...
Zfish    27 EHFHL---------DLKV--------DFLQKSISGTETIELQCIQDSQSELQLDIHP---SLSVH 71

  Fly    82 EITLSQIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSSY 146
            ||||||...:.|....:       |.||....|  .||.    :....||:..:.|||    ..|
Zfish    72 EITLSQNARDWTRTEFL-------TQDFTSYGT--TLLV----KFPTAFSSDDKLQLA----IRY 119

  Fly   147 VNTVANETRWIS------------VTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNM 199
            ..|......|:.            .||.:....|..|||||.|..|::::..:...:.:|.:  |
Zfish   120 TATDGPGVCWLEPEQTAGKLKPYVFTQGQAVLNRSCFPCFDTPAVKSTYSAAVQVPEGFTAV--M 182

  Fly   200 PVNETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNGTLFRTWARP--------- 255
            ..|:....::...:::| .|..:|  .||||.::.|.    .:...|...|.|..|
Zfish   183 SANKWEQRKADGAFLFT-MEHPIP--AYLVALAVGDL----QSAEVGPRTRVWTEPCLLQAAKQE 240

  Fly   256 --NAIDQCDYAAE--LGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLY 316
              |.|:......|  .||.|...|:.||     :|       |.|..|.||| ..:||....||
Zfish   241 YDNVIEDFLSVGEKLFGPYVWGRYDVLF-----MP-------PSFPFGGMEN-PCLTFVTPCLL- 291

  Fly   317 SPEYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQL 381
                   ...:..|:::.||:.|.|||||||...|.|.||||||..|.......:::.:..|...
Zfish   292 -------AGDRSLADVIVHEICHSWFGNLVTNATWGDFWLNEGFTMYAQRRVCRELYGEAYTCLE 349

  Fly   382 ESMSNLLTIFRKDSLESSHPISR---PIEMTSQISESFDEISYQKGSSVIR-MMHLFLGEEAFRT 442
            .:....|.....|:....||:::   .||......::::|..|:||...:. :.||...:..|.|
Zfish   350 AATGKALLRQHMDNTGEDHPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLTGDQSRFDT 414

  Fly   443 GLKSYLEKYTYKNAEQDNLWESLTQAAHKTGSLPKDYNIKTI----MDSWTLQTGYP--VINVTR 501
            .||:|:||:.:::...::..|...:...:.    |:.|:..|    .|||....|:|  |.:::.
Zfish   415 FLKAYVEKFKFRSVLAEDALEFYLEYFPEL----KERNVHKIEGLDFDSWLNVPGWPPYVPDLSA 475

  Fly   502 DYT-SRTAKLSQERYLL-NTDVSRAHKGCWWVPLSYTNQEEKDFNNTAPKEWMECTETGESVPKT 564
            ..| .:.|:|..|::|. |.|:                                     ||:.||
Zfish   476 GQTLMKPAELLAEKWLSHNLDL-------------------------------------ESICKT 503

  Fly   565 IHDLPGPDQWVIFNNQLSAPYKVNYDAQNWKLLIETLNSEDYHSIH----VVNRAQLIDDVLYFA 625
                                     |.::||         .|.:::    ::.::.|.|..|
Zfish   504 -------------------------DLKSWK---------TYQTVYFLDRILEKSPLPDGNL--- 531

  Fly   626 WTGEQDYEIALQVISYLERERELLPWKSAFDNLQFVSGILRQTPNFRFFKNF-----TRRLITPI 685
               ::..|...|:|.....|.: :.|.......|:       :|.|:..::|     .::...|:
Zfish   532 ---KKLEECYSQIIKSNNAELK-VRWAQIVAKNQY-------SPGFQHIRDFLSSQGKQKYTLPV 585

  Fly   686 YEHL-NGINDTVA 697
            |..| ||..:|.|
Zfish   586 YRALWNGSEETKA 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11951	NP_001350853.2	M1_APN-Q_like	35..490	CDD:341064	121/493 (25%)
		ERAP1_C	574..902	CDD:463368	23/134 (17%)
rnpep	NP_001002741.2	None